Recombinant Human Keratinocyte Growth Factor-2

These Recombinant Human Keratinocyte Growth Factor-2 is a novel human protein that stimulates the repair of injured mucosal tissues. KGF-2 directly promotes wound-healing by stimulating the proliferation, migration and differentiation of epithelial cells, and has direct chemotactic effects on tissue remodeling. KGF-2 also appears to result in less scarring.
Recombinant Human KGF-2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 170 amino acids with molecular weight of about 19.3kD. Recombinant human KGF-2 is highly related to KGF-1(FGF-7) and binds to the same receptor as KGF-1 and shares 57% sequence homology. Recombinant KGF-2 is purified by proprietary chromatographic techniques.
Source i Escherichia Coli.
Physical Appearance i Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation i Lyophilized from a concentrated (1mg/ml) solution in water containing 40mM Sodium Phosphate buffer, pH 7.4 , 20 mM NaCl.
Solubility i It is recommended to reconstitute the lyophilized KGF -2 in sterile 18MIC-cm a H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Stability i Lyophilized KGF-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18a . Upon reconstitution KGF-2 should be stored at 4a between 2-7 days and for future use below -18a . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).