Recombinant Human Bone Morphogenetic Protein-2

These Recombinant Human Bone Morphogenetic Protein-2 is a homodimer, linked by a single disulfide bond. The monomers have three intrachain disulfide bridges, forming a so-called cystine knot. In vivo, the monomer is synthesized as a large precursor, which after dimerization, is prote-olytically cleaved releasing the smaller C-terminal fragment forming the mature dimer .
Our product produced in genetically engineered Eschericha coli is a non-active aggregated form. After refolding and purification, the recombinant human bone morphogenetic protein-2 is active and with high homogeneity.
Source :Escherichia Coli.
Physical Appearance :Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation :Lyophilized from a concentrated (1mg/ml) solution in water containing 20mM Sodium Acetic buffer, pH4.0.
Solubility :It is recommended to reconstitute the lyophilized BMP-2 in distilled H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Stability :Lyophilized BMP-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18a . Upon reconstitution BMP-2 should be stored at 4a between 2-7 days and for future use below -18a . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).