Bispecific Antibody Production

Our organization hold expertise in providing services of Bispecific Antibody Production. As an industry leader in antibody engineering field, experts from Creative Biolabs has developed CeativeAbTM antibodies in order to increase the efficacy of current therapeutic antibodies. Bispecific antibodies (BsAbs) are bioengineered antibodies that contain two different binding sites within a single molecule, which can specifically bind two different types of antigen. The most widely used application of bi-specific antibody is in cancer immunotherapy, which create a therapeutic treatment approach for diseases with specific medical needs.
Compared with traditional antibodies, bispecific antibodies have many advantages. The two arms can bring an antigen-expressing cell in close proximity to a killing cell and thus destroy the tumor cell; the two binding sites can significantly increase affinity or internalization rates of particular antigens on a cell's surface by binding to two different epitopes on an antigen; they usually have a higher cytotoxic potential to bind to antigens with low expression level. Binding tumor cells using a bi-specific antibody-drug conjugate (ADC) also holds great promise for the future development of therapeutics for a variety of diseases.