Rosuvastatin 10/20 Mg

Rosuvastatin Rosuvastatin structure.svg Rosuvastatin-3D-balls.png Clinical data Pronunciation /roA A A A suA A vA A stA A tA Aan/ roh-SOO-vA A -stat-in Trade names Crestor, Rosulip, Zuvamor AHFS/Drugs.com Monograph MedlinePlus a603033 Pregnancy category AU: D US: X (Contraindicated) Routes of administration By mouth (tablets) ATC code C10AA07 (WHO) Legal status Legal status AU: S4 (Prescription only) UK: POM (Prescription only) US: AcA A -only In general: AcA A (Prescription only) Pharmacokinetic data Bioavailability 20%[1] Protein binding 88%[1] Metabolism Liver: CYP2C9 (major) and CYP2C19-mediated; ~10% metabolized[1] Metabolites N-desmethyl rosuvastatin (major; 1/6AcA A 1/9 of rosuvastatin activity)[2] Elimination half-life 19 hours[1] Excretion Faeces (90%)[1] Identifiers IUPAC name[show] CAS Number 287714-41-4 Yes PubChem CID 446157 IUPHAR/BPS 2954 DrugBank DB01098 Yes ChemSpider 393589 No UNII 413KH5ZJ73 KEGG D01915 No ChEBI CHEBI:38545 No ChEMBL CHEMBL1496 No PDB ligand I (PDBe, RCSB PDB) ECHA InfoCard 100.216.011 Edit this at Wikidata Chemical and physical data Formula C22H28FN3O6S Molar mass 481.539 3D model (JSmol) Interactive image SMILES[show] InChI[show] NoYes (what is this?) (verify) Rosuvastatin , is a member of the drug class of statins, used in combination with exercise, diet, and weight-loss to treat high cholesterol and related conditions, and to prevent cardiovascular disease.