White Accudx Cq Hs Crp Test Kit Pack Of 25 Tests

ACCUDx CQ hs-CRP+CRP Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of C-reactive protein (CP) in serum, plasma or whole blood. Measurement of CRP is useful for the detection and evaluation of infection, tissue injury and inflammatory disorders. Measurement of high sensitivity CRP (hs-CRP), when used in conjunction with traditional clinical laboratory evaluaticn of acute coronary syndromes (ACS), may be useful as an independent marker of prognosis for recurrent events in patients with stable coronary disease or ACS.

INTRODUCTION
C-reactive protein is an acute-phase reactant that precipitates with Pneumococcal -polysaccharide and is a non-specific immune response component. CRP nas wide disinibution in our body and is an acute-viiase protein produced in the liver in response to microbial infection or tissue injury. hs-CRP can be used to detect lower concentrations of CRP in serum, plasma or whole blood. Studies reveal that hs-CRP levels correlate with Atherosclerosis and Acute Myocardial Infarction, hs-CRP is an inflammation
"marker" for ACS and is helpful for primary risk assessment of cardiovascular disease. Its combination with the ratio of total cholesterol to HDL-C is more accurate than other risk factor in predicting cardiovascular disease.
The American Heart Association and US Centers for Disease Control and Prevention have advocated hs-CRP as a predictor of cardiovascular disease (CVD) to define risk groups: less than 1.0 mg/L indicates low risk, 1.0 to 3.0 mg/L means moderate risk, and above 3.0 mq/L (lower than 10mg/L) strongly suggests a high risk of CV/D. Moreover, highe: CRP levels are found in late pregnant women, mild inflammation and viral infections (10-40 mg/L). active inflammation, bacterial infection (40-200 mg/L), severe bactenal
infections and burns (>200 mg/L).

PRINCIPLE
The test uses an anti-human CRP monoclonal antibody conjugated with fluorescence latex and another anti-human CP monocional antibody coated on the test line. After the sample has been applied to the test strip, the fiuorescence latex-labelled anti-human CRP monoclonal antibody binds with the CRP in sample and forms a marked antigen-antibody complex. This complex moves to the test detection zone by capillary action. Then, the marked antigen-antibody complex is captured on the test line by the anti-human CRP monoclonal antibody. The fluorescence intensity of the test Nine increases in proportion to the amount of CRP in sample. Then, the test card is inserted into ACCUDx CQ Immunofluorescence Quantitative Analyzer. The concentration of CRP in sample will be measured and displayed on the screen. The value will be stored in ACCUDx CQ Analyzer. The result can be transmitted to the laboratory or hospital information system.