Sterilization In Place (Sip) Systems

Pharmaceutical Sterilization-in-Place (SIP) systems are made to sanitize a selection of process equipment after a batch of product is completed. Equipment such as bioreactors, fermentors and the enclosed tubing must be cleaned and/or sterilized before a new production cycle .
The steam pressures seen are generally in the 20-30 psi range with corresponding temperatures ranging from 121A C to 135A C. The relationship between pressure and temperature is a given, however sterilization times will range relying on the temperature and the nature of the item being sterilized. In general, the lower the temperature, the longer it takes to sterilize. The sterilization time/temperature relationship in a typical SIP process will occur at about 121A C for 30-40 minutes. Moreover, all these products are being offered to our clients at affordable price.