Sevelamer is used to control high blood levels of phosphorus in people with chronic kidney disease who are on dialysis (medical treatment to clean the blood when the kidneys are not working properly). Sevelamer is used to control high blood levels of phosphorus in people with chronic kidney disease who are on dialysis (medical treatment to clean the blood when the kidneys are not working properly). Sevelamer is in a class of medications called phosphate binders. It binds phosphorus that you get from foods in your diet and prevents it from being absorbed into your blood stream. Sevelamer inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood. Sevelamer inhibits the absorption of phosphate from the intestine and lower the phosphate levels in the blood. Sevelamer is used to control blood phosphate level in patients that are on dialysis treatment. You must take it with food and stick to the diet prescribed by your doctor. You may develop low levels of calcium, folic acid, and vitamins A,D,E, and K in your blood. Your doctor may prescribe supplements, if necessary. Avoid taking any other medicine 1 hour before or 3 hours after taking Sevelamer. Inform your doctor if you have nausea, vomiting, constipation, pain in the abdomen, or if you have undergone any major stomach surgery It is important to take Sevelamer as patients undergoing dialysis cannot control the phosphate levels in their blood, especially after a meal. When the level of phosphate exceeds above the range in the blood, it may cause problems such as itchy skin, red eyes, high blood pressure, bone pain, and also increase the risk of fractures. These increased serum phosphate levels are reduced by Sevelamer, as it binds phosphate from food in the digestive tract. Sevelamer is used in the management of hyperphosphatemia in adult patients with stage 4 and 5 chronic kidney disease (CKD) on hemodialysis. Its efficacy at lowering phosphate levels is similar to that of calcium acetate, but without the accompanying risk of hypercalcemia and arterial calcification.[4][5] In patients with CKD, it has also been shown to reduce LDL and cholesterol.[Sevelamer carbonate is a pharmaceutical phosphate amine created as an alternative to sevelamer hydrochloride. It is a polymeric structure with an anion exchange resin, and it is chemically known as poly(allylamine-co-N, N Diallyl-1,3 diamino-2-hydroxyproline). The drug is insoluble in water but is hygroscopic. Sevelamer carbonate is a film-coated tablet for oral administration and is used to treat hyperphosphatemia in CKD (chronic kidney disorders) patients on peritoneal dialysis. Sevelamer carbonate is indicated for oral administration to control hyperphosphatemia or high serum phosphorous levels in children (six years and above) and adults suffering from chronic kidney disorders (CKD) on dialysis.Hyperphosphatemia condition arises when there is too much phosphate in the blood. This may occur due to various conditions such as hypoparathyroidism, advanced chronic kidney disease, and respiratory and metabolic acidosis. Hyperphosphatemia does not cause symptoms but can lead to hypocalcemia (removal of calcium from blood and bones) and cause various symptoms. Hyperphosphatemia can be managed with dietary changes, medications, and dialysis.Sevelamer is used to control high blood levels of phosphorus in people with chronic kidney disease who are on dialysis (medical treatment to clean the blood when the kidneys are not working properly). Sevelamer is in a class of medications called phosphate binders. It contains sevelamer, which belongs to a class of medicines known as phosphate binders. It works by binding to the phosphates and reduces the levels of phosphate in the blood. Sevelamer should be taken as directed by the doctor and in doses and duration as prescribed Sevelamer (Renagel, Genzyme) is indicated for the treatment of hyperphosphatemia in adult patients.