Country of Origin : China
Acridine based chemiluminescence reagents
mainly include acridine ester and acridine sulfonamide.
Acridine ester is a very important chemiluminescence reagent with high quantum yield.
At present, the synthesis of acridine ester dmae-nhs can be divided into seven steps.
The traditional seven step method was optimized and a new five step method was developed to synthesize acridine salt.
Acridine ester dmae-nhs was synthesized from 3,5-dimethyl-4-hydroxybenzoic acid and acridine 9-carboxylic acid by esterification, condensation, hydrolysis, succinylation and methylation.
The purity of dmae-nhs was over 99%.
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