Osthole - 99% Pure Extract, Enhances Libido And Supports Male Sexual Function

Our range of Osthole - also spelled osthol - is a kind of coumarins. Osthole is found in cnidium monnieri and several other plants. Osthol could increase androgen, gonadotropin and nitric oxide synthase (NOS) activity. Osthole is a libido stimulator. Researchers investigate the cavernosal relaxant effect of osthole, has been long used in China as a herbal medicine to improve male sexual dysfunction. The data suggested that osthole posseses a relaxant effect on rabbit corpus cavernosal tissues which is attributable to the release of NO from sinusoidal endothelium and to the potentiation of the cGMP and/or cAMP signal mediating relaxation of cavernosal smooth muscle by inhibiting phosphodiesterase".
Osthole benefit for fatty liver.
The effect of osthole, isolated from Angelica pubescens, on the contraction of guinea-pig trachea was studied. Osthole, theophylline and higher concentrations of nifedipine suppressed the contraction response curves of tracheal smooth muscle caused by carbachol, prostaglandin F2 alpha (PGF2 alpha), U46619 (thromboxane A2 analogue) and leukotriene C4 (LTC4) in a concentration-dependent manner. It is concluded that osthole exerts a non-specific relaxant effect on the trachealis by inhibiting the cAMP and cGMP phosphodiesterases.
CAS Registry Number: 484-12-8