Fumed Silica

4

Other

Aerosil Fumed Silica

SYLOIDA,A(r) 244 FP SilicaSilica Excipient for Pharmaceutical ApplicationsHigh EfficiencySYLOIDA,A(r) 244FP silica is highlyefficient in many pharmaceuticalapplications due to its unique particlestructure and morphology. It has ahighly developed network of poresthat provide access to the ultrahigh surface area which defines itAC/AEURAtmsperformance. The result is a productwhich is:AC/AEURAC/ Easy to incorporate providing moreuniform dispersion of actives andimproved content uniformityAC/AEURAC/ High in adsorptive capacityAC/AEURA"bothfor hydrophilic and hydrophobiccompoundscontinued on backApplicationsGlidantTabletting AidCarrier for Active IngredientsThickening, Gelation, and SuspensionMoisture ScavengerPROPERTY BENEFITHigh internal porosity andsurface areaHigh efficiency for lower costsHigh adsorptive capacity Carry higher level of actives/reduced level of inactivesLow to moderate density forlower dustCleaner work areas and less chanceof cross contaminationControlled particle sizedistributionMore uniform blending resulting inimproved content uniformityGlidantSYLOIDA,A(r) 244FP silica should beincorporated in your formulation atlevels from 0.25-1.0% to achievea free flowing powder that will notstick to the walls of your transfersystem, tabletting and otherequipment. Uniform powder flowis critical to achieving a consistentproduct dosage, whether the productis a capsule, tablet or other oraldosage form of pharmaceutical. Theadsorptive properties of SYLOIDA,A(r)244FP silica, along with its ease ofincorporation, make it more effectivethan other types of glidants used inpharmaceuticals.TablettingSYLOIDA,A(r) 244FP silica incorporatedinto your powder during thegranulation process ensures uniformflow through your equipment.This results in higher consistencyduring the tabletting process andimprovement in the followingparameters:AC/AEURAC/ Content uniformityAC/AEURAC/ Structural stabilityAC/AEURAC/ Reduced friability and improvedhardnessAC/AEURAC/ Resistance to capping, laminationand stickingAC/AEURAC/ Controlled drug release rateDuring the compression cycle of thetabletting process, liquid ingredientscan be forced to the surface or evencaused to exude from the tablet. Thelarge internal porosity of SYLOIDA,A(r)244FP silica provides greatercapacity for any liquid ingredients thatmay be included in your formulation,which can prevent the occurrence ofthe above problems

Industrial

10 Days

7-10 Days