Zoledronic Acid By Fuhuiyuan Industrial Co. Limited

Zoledronic acid is a widely used chemical in several industrial sectors. We are a profound manufacturer of the same to our highly valued clients. We make use of superior quality chemical compounds in its making at our unit along with the help of state-of-the-art machinery. Zoledronic acid is appreciated by our clients for its unmatched quality, safe usage, effectiveness and a long life. This has gained us huge appreciation from our customers in both national as well as overseas markets.  Technical Specifications :  Item Specification Result Appearance White or almost white crystalline powder White crystalline powder Solubility Practically insoluble in ethanol, slightly soluble in water, sparingly soluble in NaOH(0.1M) Conforms Identification IR: absorption spectrum should be consistent with the spectrum obtained with that of the RS. Conforms The retention time of principal peak in chromatogram obtained with the test solution is identical with that obtained with reference solution Conforms It gives reaction of phosphate Conforms Clarity and color of solution The solution should be clear and colorless, if not, not more inrensely turbid than No.1 reference solution and not more intensely colored than reference solution of yellow-2. Conforms pH 2.0-3.5 2.9 Residue solvents n-hexane 0.029% max(g/g) 0.000039% Acetonitrile 0.041% max(g/g) Undetectable Chlorobenzene 0.036% max(g/g) Undetectable Phosphate 0.4% max Conforms Phosphite 0.4% max Conforms Chloride 0.04% max Conforms Loss on drying 5.5-7.5% 6.3% Heavy metals 10ppm max Conforms Related substances Any other single impurity:0.5% max 0.27% Total impurity:1.0% max 0.50% Assay 98.5% min(on dried basis) 99.6% Microbial limit Total aerobic microbial count:1000cfu/g max 10cfu/g Total combined yeast/molds count:100cfu/g max 10cfu/g Escherichia coli: absent undetectable Conclusion:The batch tested complies with the standard .