Stony Brown Xbira 250 Tablets

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Trade name : Xbira 250
Abiraterone acetate is the generic name for the trade name drug Zytiga. In some cases, health care professionals may use the trade name Zytiga when referring to the generic drug name abiraterone acetate.

Drug type:
Abiraterone acetate is a type of hormone therapy. This medication is classified as an adrenal inhibitor". (For more detail, see How abiraterone acetate Works below)

What Abiraterone Acetate is Used For:
Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.

Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.

How Abiraterone Acetate is Given:
Abiraterone acetate is a pill, taken by mouth. It is taken once a day.
It must be taken on an empty stomach [2 hours after a meal, or one hour before]
It should be taken at approximately the same time each day.
Prednisone [10mg daily] should be taken along with abiraterone acetate.
The amount of abiraterone acetate you receive depends on many factors. Your doctor will determine your dose and schedule

Abiraterone Acetate Side Effects:
Important things to remember about the side effects of abiraterone acetate:
Most people will not experience all of the abiraterone acetate side effects listed.
Abiraterone acetate side effects are often predictable in terms of their onset, duration, and severity.
Abiraterone acetate side effects are almost always reversible and will go away after therapy is complete.
Abiraterone acetate side effects may be quite manageable. There are many options to minimize or prevent the side effects of abiraterone acetate.

The following side effects are common (occurring in greater than 30%) for patients taking abiraterone acetate:
Fluid Retention
Increased triglycerides
Increased liver enzymes (AST)

These side effects are less common (occurring in 10-29%) side effects for patients receiving abiraterone acetate:
Joint swelling / discomfort
Decreased levels of potassium in your blood (hypokalemia)
Peripheral Edema (swelling of the hands/feet)
Muscle aches / discomfort
Decreased levels of phosphorus in your blood (hypophosphatemia)
Hot flashes
Diarrhea
Urinary tract infections
Cough
Increased ALT (liver enzyme)

Abiraterone acetate works by inhibiting specific "enzymes" in your adrenal glands that are responsible for making androgens. For this reason, there is an increased risk of over production of mineralcorticosteroids in your body while on abiraterone acetate. As a result, abiraterone acetate may cause hypertension [high blood pressure], hypokalemia [low levels of potassium in the blood], and fluid retention. Because of this risk, abiraterone acetate should be used cautiously in patients with a strong cardiovascular history, and patients should be monitored closely for these symptoms. Dosing along with prednisone will decrease the risk of mineralocorticoid excess.
Not all side effects are listed above. Side effects that are very rare -- occurring in less than about 10 percent of patients -- are not listed here. But you should always inform your health care provider if you experience any unusual symptoms.

When to contact your physician or health care provider:
Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:
Fever of 100.4A A F (38A A C or higher, chills)
Chest Pain or Irregular heart beats
Difficulty breathing
Inability to urinate for 8 or more hours

Always inform your health care provider if you experience any unusual symptoms.