Tenoxicam Micronised - Dosage Form: Tablet

5

3

Tablets

Solid

Liquid

5 Days

1 Days

7 Days

Slightly soluble in water; soluble in organic solvents such as DMSO, methanol, ethanol

Solubility in Water: Very slightly soluble in water. It has limited solubility in aqueous solutions, which is why it is often formulated in sodium salts or micronized for better absorption in pharmaceutical formulations. Solubility in Other Solvents: Soluble in alkaline solutions, such as sodium hydroxide or sodium bicarbonate. Slightly soluble in acetone and ethanol. Practically insoluble in chloroform and ether. Solubility for Injection: When preparing for injection, Tenoxicam is typically reconstituted in an alkaline solution (like sodium hydroxide), which increases its solubility. Formulation Considerations: Due to its low water solubility, Tenoxicam is often formulated in micronized or salt forms to improve its dissolution rate, especially in oral tablets and injectable preparations.

Not applicable (solid form)

5.0 to 7.0.

29420090

2942.00.90

261-605-8

261-689-2

Yellow

yellow to yellowish-orange

212-216 AdegC

154 158 C

Other, Store in tightly closed container, protected from light, at room temperature

Room Temperature

<0.001%

20 ppm

4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

Other

Pharmaceutical Intermediates

Used as a non-steroidal anti-inflammatory drug (NSAID), mainly for pain and inflammatory disorders.

Tenoxicam is a non-steroidal anti-inflammatory drug (NSAID) used primarily for its analgesic, anti-inflammatory, and antipyretic propertiesRheumatoid ArthritisReduces joint pain, swelling, and stiffness.OsteoarthritisHelps relieve pain and improve joint mobility.Ankylosing SpondylitisEases inflammation and stiffness in the spine.Acute Musculoskeletal PainUsed in short-term conditions like sprains, strains, or back pain.Post-operative PainSometimes used as an injectable NSAID to control pain after surgery.Gout (Acute Attack)Reduces inflammation during acute episodes. Routes of AdministrationOral tabletsIntramuscular injection (sterile powder form reconstituted with solvent)Rectal suppositories (less common)Precautions & Side EffectsCommon: Gastric irritation, nausea, headache, dizzinessSerious: GI bleeding, kidney impairment, cardiovascular risks (especially with long-term use)Contraindicated in: Peptic ulcer, severe kidney or liver disease, pregnancy (especially 3rd trimester)

Yellow crystalline powder

Yellow to yellowish-orange