Roche Cardiac Trop Tsensitive Test

Cardiac troponin T is a muscle structural protein which is released in the event of cell damage (necrosis) to the myocardium. The TROPT Sensitive test is designed for qualitative determination of cardiac troponin T in the blood as an aid for risk stratification of patients with unstable angina pectoris and for diagnosis of myocardial infarction (ST segment elevation myocardial infarction (STEMI) and Non ST segment elevation myocardial infarction (NSTEMI)) among patients suffering from thoracic pain or who are suspected of experiencing myocardial infarction or acute coronary syndrome in accordance with the redefinition of myocardial infarction by the ESC (European Society of Cardiology) and the ACC (American College of Cardiology)

as well as the guidelines laid down by the ACC and the AHA (American Heart Association).


A negative troponin T result does not rule out myocardial infarction as the release of troponin T from the damaged myocardial cells into the circulating blood occurs with time delays which vary from person to person.

The release kinetics of troponin T after an infarction should therefore be taken into account when interpreting the test results. Troponin T can first be detected in the blood after a time period of 2 to more than 10 hours after the onset of symptoms. This means that a negative troponin T result does not rule out myocardial infarction. Typical or atypical symptoms and a negative Trop T result call for further diagnostic measures to be applied, including more troponin T tests. Due to its release kinetics, troponin T can be detected for up to 14 days after onset of cardiac infarction.