Regen-d 150

Epidermal Growth Factor (EGF) is a small 53 amino acid residue long protein that contains three disulfide bridges. It is a small mitogenic protein that is involved in normal cell growth and wound healing. REGEN-D 150 is manufactured using recombinant DNA technology.

EGF - Signal Transduction Pathway
Epidermal Growth Factor (EGF) peptide induces cellular proliferation through the EGF receptor, which has a tyrosine kinase cytoplasmic domain, a single transmembrane domain and an extracellular domain involved in EGF binding and receptor dimerization. The proliferative effects of EGF are signaled through several pathways. Binding of EGF results in EGF receptor dimerization, autophosphorylation of the receptor, and tyrosine phosphorylation of other proteins. EGF receptor activates MAP kinase pathway, ultimately causing phosphorylation of transcription factors that contribute to proliferation.