Phloretin

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Synonyms: 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one, Dihydronaringenin, Phloretol,A
Cas#: 60-82-2
M.W.: 274.27
A natural flavonoid, phloretin is extracted from Prunus mandshurica and has demonstrated anti-inflammatory and immunomodulatory activities from previous studies. For example, phloretin has been found to prevent T cell activation by downregulating expression of CD69 and CD25 and reduce activated macrophage-induced inflammation by suppressing the nuclear translocation of NF-I B and phosphorylation in the MAPK signaling pathway. Furthermore, phloretin can implement its antioxidative function to further reduce the inflammation. With its anti-inflammatory and antioxidative properties, phloretin could be a good candidate as an Rheumatoid arthritis (RA)A remedy agent.
Format: off-white to white powder
Package: 1KG