Nomegestrol Acetate - 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione 17-acetate, Selective Progestin With Antigonadotropic Effects

Our provided Nomegestrol Acetate (INN; Lutenyl), or 19-normegestrol acetate, is a steroidal progestin with additional antigonadotropic effects which was introduced in 1986 and is used as a hormonal contraceptive.[1][2] Unlike many other steroidal progestogens, it is selective for the progesterone receptor, lacking any significant affinity for other steroid receptors such as the androgen, estrogen, glucocorticoid, and mineralocorticoid receptors. As a result, it does not possess any androgenic, estrogenic, glucocorticoid, or mineralocorticoid effects. However, at sufficiently high doses it does have potent antiestrogenic and antiandrogenic effects due to its progesterone receptor-mediated antigonadotropic properties.[3][4]

The combination with estradiol is also used as a hormonal contraceptive and approved in Europe under the name Zoely.[5]

CAS Name: Nomegestrone Acetate
Alias: 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione 17-acetate; Nomegestrol 17-acetate; (17alpha)-17-acetyl-6-methyl-3-oxoestra-4,6-dien-17-yl acetate
EINECS NO.: 261-379-8
Molecular weight: 370.4819
Boiling point: 507.3A C at 760 mmHg
Density: 2.06E-10mmHg at 25A C
Flash point: 219.8A C
17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione 17-acetate; Nomegestrol 17-acetate; (17alpha)-17-acetyl-6-methyl-3-oxoestra-4,6-dien-17-yl acetate.

Clients can avail this Nomegestrol Acetate at industry leading prices from us.