Levamisole 150mg Bolus

Being pioneers of the industry, we are manufacturing, exporting and supplying Levamisole 150mg Bolus to our customers in Shijiazhuang, Hebei, China.
(Item No.: TB004)

Composition:
Contains per bolus.:
Albendazole : 150 mg Carriere ad 6g
Albendazole : 600 mg Carriere ad 6g
Albendazole : 1000 mg Carriere ad 6g
Pharmacology
Levamisole is an imidazothiazole that acts by interfering with parasite nerve transmission causing muscular paralysis. It stimulates the parasympathetic and sympathetic ganglia in susceptible worms. At higher levels, levamisole interferes with nematode carbohydrate metabolism by blocking fumarate reduction and succinate oxidation. The net effect is a paralyzing effect on the worm which is then expelled alive.

Pharmacokinetics
Levamisole is absorbed from the gut after oral dosing and through the skin after dermal application, although bioavailabilities are variable. It is reportedly distributed throughout the body. Levamisole is primarily metabolized with less than 6% excreted unchanged in the urine. Plasma elimination half-lives have been determined for several veterinary species: Cattle 4-6 hours; Dogs 1.8-4 hours; and Swine 3.5-6.8 hours. Metabolites are excreted in both the urine (primarily) and feces.
Indications
Levamisole is indicated for the treatment of many nematodes in cattle, sheep & goats, swine, poultry.