Itraconazole

CAS number
84625-61-6

Chemical Formula
C35H38Cl2N8O4

"For the treatment of the following fungal infections in immunocompromised and non-immunocompromised patients: pulmonary and extrapulmonary blastomycosis, histoplasmosis, aspergillosis, and onychomycosis
Itraconazole is an imidazole/triazole type antifungal agent. Itraconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethylation via the inhibition of the enzyme cytochrome P450 14α-demethylase. This enzyme converts lanosterol to ergosterol, and is required in fungal cell wall synthesis. The subsequent loss of normal sterols correlates with the accumulation of 14 α-methyl sterols in fungi and may be partly responsible for the fungistatic activity of fluconazole. Mammalian cell demethylation is much less sensitive to fluconazole inhibition. Itraconazole exhibits in vitro activity against Cryptococcus neoformans and Candida spp. Fungistatic activity has also been demonstrated in normal and immunocompromised animal models for systemic and intracranial fungal infections due to Cryptococcus neoformans and for systemic infections due to Candida albicans."

Company Details

Wholesaler, Trader, Distributors and supplier of Pharmaceutical finish formulation, Raw materials, intermediates, Excipients, Ayurvedic products. we are supplying generic medicines for almost all of the therapeutic classes such as Antiviral, Antimalarial, Antifungal, Anticancer (Oncology), Erectile Dysfunction, Sex Enhancement, Cardiovascular, Beta-lactamAntibiotics, NSAIDs, Antidiabetic, Antiasthmatic, Antiemetic, Anesthetic, Antacid, Painkillers, Antiallergic, Antihypertensive, Dermatological, Ophthalmic, Gastricmedicines in the form of Coated and Uncoated Tablets, Effervescent Tablets, Sustained Release (SR) Tablets, Chewable Tablets, Flavored Tablets,Capsules, Derma Care,Transdermals, Topical Preparations, Dry Syrups, Vials,Oral Liquids, Suspension, Gel, Creams, Lotions, Ointments, Dry Injections, Drops, Inhalers andExternal Formulations.

• BUSINESS TYPE Exporter, Manufacturer, Distributor, Supplier, Trading Company
• EMPLOYEE COUNT 30
• ESTABLISHMENT 2018
• ANNUAL TURNOVER Rs 70 Lakhs
• WORKING DAYS Monday To Sunday
• PAYMENT MODE Telegraphic Transfer (T/T)