Intermediates Acadesine - Cas 2627-69-2, Assay 98%, White Powder, Einecs 220-097-5, C9h14n4o5 , Ampk Activator For Cardiovascular Research
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Product Specifications
| CAS Number | 2627-69-2 |
| Alias | AICAR, AICA-Riboside |
| Assay | 98% |
| EINECS | 220-097-5 |
| Molecular Formula | C9H14N4O5 |
| Molecular Weight | 258.23 |
| Melting Point | 214-215 °C |
| Storage | -20°C |
| Solubility | Water, DMSO |
| Appearance | White powder |
| Usage | Pharmaceutical intermediate for cardiovascular disease treatment |
| Features | High purity, Pharmaceutical grade, Cardiovascular research, AMPK activator, Inhibits PPAR |
Product Overview
Key Features
We are engaged in distributing excellent quality Intermediates Acadesine in Durban, KwaZulu Natal, South Africa.
CAS: 2627-69-2
Alias: AICAR;AICA-RIBOSIDE;AMPK;Z-RIBOSIDE
CAS: 2627-69-2
Assay: 98%
EINECS: 220-097-5
M.F.: C9H14N4O5
M.W.: 258.23
M.S.:
M.P.: 214-215 A C
Storage instructionsi Store at -20A C (desiccating conditions).
Solubility overviewi Soluble in water to 50 mM and in DMSO to 100 mM (with
heating)
Properties: white or off-white powder.
Usage: pharmaceutical intermediates.For the treatment of cardiovascular
diseases.
Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
CAS: 2627-69-2
Alias: AICAR;AICA-RIBOSIDE;AMPK;Z-RIBOSIDE
CAS: 2627-69-2
Assay: 98%
EINECS: 220-097-5
M.F.: C9H14N4O5
M.W.: 258.23
M.S.:
M.P.: 214-215 A C
Storage instructionsi Store at -20A C (desiccating conditions).
Solubility overviewi Soluble in water to 50 mM and in DMSO to 100 mM (with
heating)
Properties: white or off-white powder.
Usage: pharmaceutical intermediates.For the treatment of cardiovascular
diseases.
Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
Company Details
AWPS AGRO-CHEM SAPRO(PTY)LTD., Established in 2005 at Durban in KwaZulu Natal, is a leading Distributor of Pharmaceutical Manufacturing Facilities in South Africa. AWPS AGRO-CHEM SAPRO(PTY)LTD. is one of Trade India's verified and trusted sellers of listed products. With extensive experience in supplying and trading Intermediates Acadesine, AWPS AGRO-CHEM SAPRO(PTY)LTD. has made a reputed name for itself in the market with high-quality Intermediates Acadesine, etc.
Focusing on a customer-centric approach, AWPS AGRO-CHEM SAPRO(PTY)LTD. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Manufacturing Facilities in bulk from AWPS AGRO-CHEM SAPRO(PTY)LTD. at Trade India quality-assured products.
Focusing on a customer-centric approach, AWPS AGRO-CHEM SAPRO(PTY)LTD. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Manufacturing Facilities in bulk from AWPS AGRO-CHEM SAPRO(PTY)LTD. at Trade India quality-assured products.
Business Type
Distributor
Establishment
2005
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Seller Details
Durban, KwaZulu Natal
Name
Mr. Jacques Lotter
Address
Ridgeside Office Park, 69 Richefond Circle Umhlanga Rocks, Durban, KwaZulu Natal, 4001, South Africa
Pharmaceutical Manufacturing Facilities in Durban
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