Glimepiride Sulfonamide - Off-white To White Powder, 98% To 102% Assay | Antidiabetic Intermediate With Low Impurity Levels

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Product Name -- Glimepiride Sulfonamide
Cas No -- 119018-29-0
Dosage Form -- Powder
Chemical Name -- N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
Non propriety Names -- Sulfonamide for Glimepiride Pure
Molecular Formula -- C16H21N3O4S
Molecular Weight -- 351.4218

Product specification

Description -- Off-white to white powder
Solubility -- 2.0 % Clear solution in DMF
Melting Point -- 178 0 C a 183 0 C
Chloride -- NMT 0.5 % w/w
L.O.D. -- NMT 0.5 % w/w
Assay By -- 98.0 % To 102.0 % w/w (Dry Basis )
Related Substance TLC method -- By TLC
Two impurities -- individually NMT 0.5 % by TLC
Total impurities -- NMT 1.0 %
Related Substance HPLC method -- Ortho , meta isomers
individually -- NMT 0.5 %
Total impurities -- NMT 1.0 %

It is used as an intermediate for the following drug :-
Glimepiride (CAS No 93479-97-1)
Therapeutic Cat. Of This Drug :- Antidiabetic