Cetrimide Bp By Seema Biotech

1 Appearance: A clear and colorless to slightly yellow syrupy liquid Clear pale yellow syrupy liquid
2 Identification
A) Chemical test: Yellow precipitate is produced Complies
B) Chemical test: Yellow color produced slowly in chloroform layer Complies
C) Chemical test: The precipitate dissolved with difficulty Complies
3 Acidity or alkalinity: Not more than 1.0 ml of either 0.1 M HCl or 0.1N NaOH 5.0 ml
4 Relative density 0.900-1.00 0.991
5 Miscibility with ethanol: Mix a volume of the solution containing 1.6g of Cetrimide with a mixture of 2ml of water and 16ml of ethanol (96%). The solution remains clear. Complies
6 Neutral Substance: Not more than 0.4 g 0.30 g
7 Non-quaternized amines: The difference between the volumes corresponding to A and B is not more than 10 ml (2.4%, calculated as C16H35N) 9.2 ml
8 Isopropyl Alcohol: Not more than 10.0% V/V 7.48%
9 Assay (Titrimetry, %w/v): Not less than 38% w/v and not more than 42% w/v 39.56%