Ceftazidime - Highly Stable Beta-lactam Antibiotic | Effective Against Resistant Strains, Additive Synergy With Aminoglycosides

Ceftazidime is highly stable to most clinically important beta-lactamases produced by both Gram positive and Gram negative organisms; therefore, it is active against many ampicillin and cephalosporin-resistant strains. Ceftazidime has high intrinsic activity in vitro and acts at low MIC levels for most genera. MICs are not affected much by change in the inoculum sizes. In vitro, ceftazidime and aminoglycosides in combination exert additive effect with evidence of synergy against some strains.