Calcitriol Api - Micronized White To Off-white Powder, >99% Purity | Pharmaceutical Grade, Optical Rotation +83â° To +89â°, Packaged In Light-resistant Airtight Containers

3

Other, Store at 2-8AdegC, protected from light

Room Temperature

Freezer

Not applicable (decomposes before boiling)

474.91AdegC (rough estimate)

120-125 AdegC

119-1210C

(1I+-,3I2,25-Trihydroxycholecalciferol)

Calcitriol

Other, Active Pharmaceutical Ingredient (API)

Pharmaceutical Intermediates

Other

Vitamin D analogue, used to treat calcium deficiency and metabolic bone disease

Calcitriol (1I+-,25-dihydroxy Vitamin D3) is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3, the principal circulating form of Vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.[Cayman Chemical]

White to off-white crystalline powder

Powder

Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Asia

15 Days

1 Week

Export worthy packing as per customer requirement

25 kg