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Calcitriol - Active Vitamin D3 Compound | Stimulates Calcium Absorption, Reduces Pth Levels, Enhances Bone Resorption

Calcitriol - Active Vitamin D3 Compound | Stimulates Calcium Absorption, Reduces Pth Levels, Enhances Bone Resorption

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In Stock

Product Specifications

Chemical FormulaC27H44O3
Molecular Weight416.62 g/mol
Purity99%
FormPowder
CAS Number50-14-6
UsageTreats calcium disorders, secondary hyperparathyroidism in chronic kidney disease.
StorageRoom Temperature
FeaturesCalcium regulation, Bone health, PTH reduction, Absorption aid

Product Overview

Key Features

Owing to our years of industry experience and market understanding, we are leading Exporter, Manufacturer, Distributor and Supplier of Calcitriol in Mumbai, Maharashtra, India. Vitamin D analogue, Calcitriol, the active form of vitamin D (1,25 hydroxyvitamin D3), binds to and activates the vitamin D receptor in kidney, parathyroid gland, intestine, and bone, stimulating intestinal calcium transport and absorption. It reduces PTH levels and improves calcium and phosphate homeostasis by stimulating bone resorption of calcium and increasing renal tubular reabsorption of calcium. Decreased renal conversion of vitamin D to its primary active metabolite (1,25 hydroxyvitamin D) in chronic renal failure leads to reduced activation of vitamin D receptor, which subsequently removes inhibitory suppression of parathyroid hormone (PTH) release; increased serum PTH (secondary hyperparathyroidism) reduces calcium excretion and enhances bone resorption.

Company Details

G. C. Chemie Pharmie Ltd., Established in 1981 at Mumbai in Maharashtra, is a leading Exporter,Manufacturer,Supplier of Pharmaceutical Raw Materials & Ingredients in India. G. C. Chemie Pharmie Ltd. is one of Trade India's verified and trusted sellers of listed products. With extensive experience in supplying and trading Calcitriol, G. C. Chemie Pharmie Ltd. has made a reputed name for itself in the market with high-quality Calcipotriol, Calcitriol, Calcium Orotate, etc.
Focusing on a customer-centric approach, G. C. Chemie Pharmie Ltd. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Raw Materials & Ingredients in bulk from G. C. Chemie Pharmie Ltd. at Trade India quality-assured products.

Business Type

Exporter, Manufacturer, Supplier

Employee Count

35

Establishment

1981

Working Days

Monday To Sunday

GST NO

27AAACG1864F1ZS

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Seller Details

G

G. C. Chemie Pharmie Ltd.

GST

GST - 27AAACG1864F1ZS

Mumbai, Maharashtra

Manager-Export

Ms Chaitambary Bhagwat

Address

5-C, Laxmi Industrial Estate, New Link Road, Andheri (West), Mumbai, Maharashtra, 400053, India

calcitriol in Mumbai

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Product Name

Calcitriol

Calcitriol USP

Calcitriol

Buyer Feedback

3

3

Price Or Price Range

270000 INR (Approx.)

100 INR (Approx.)

Minimum Order Quantity

25 Kilograms/Kilograms

1 Kilograms/Kilograms

Molecular Formula

C27H44O3

C27H44O3

Melting Point

119-1210C

120-123C

Boiling Point

474.91AdegC (rough estimate)

Not available (decomposes before boiling)

Color

White to Almost white

Other, White to off-white

Solubility

Do you have solubility information on this product that you would like to share

Sparingly soluble in water, freely soluble in ethanol and chloroform

Structural Formula

C27H44O3

See image or chemical reference

Storage

Freezer

Other, Store at 2-8C, protected from light

Chemical Name

Calcitriol

1,25-dihydroxycholecalciferol

CAS No

32222-06-3

32222-06-3

Type

Other

Other

Grade

Other

Other

Usage

Calcitriol (1I+-,25-dihydroxy Vitamin D3) is synthesized from 7-dehydrocholesterol in humans via a non-enzymatic photochemical reaction with 290-310 nm UV light in the skin. Hydroxylation of the resulting cholecalciferol in the liver produces 25-hydroxy Vitamin D3, the principal circulating form of Vitamin D. A second, tightly regulated hydroxylation in the kidney produces calcitriol. Plasma calcitriol levels range from 10-70 pg/ml and are influenced by numerous dietary and hormonal factors. The main physiologic effects of calcitriol are to increase the absorption of calcium at the level of the intestinal epithelium, and to increase the mineralization of bone via the direct stimulation of osteoblasts.[Cayman Chemical]

Vitamin D Analog, Treatment for Hypocalcemia, Management of Osteoporosis

Purity(%)

99%

99%

Physical Form

Solid

Solid

Supply Ability

1000 Per Month

2000 Per Day

Delivery Time

1 Week

1 Days

Sold By

G. C. Chemie Pharmie Ltd.
Mumbai, Maharashtra

Seema Biotech
Mumbai, Maharashtra

Angle Bio Pharma
Ahmedabad, Gujarat

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