voice searchcamera search
Brimonidine Tartrate Grade: Medicine Grade

Brimonidine Tartrate Grade: Medicine Grade

Price: 188800.00 INR / Kilograms

(160000.00 INR + 18% GST)

Get Latest Price

MRP:

188800.00 INR / Kilograms

Weight :

25.00 Kilogram

1 Pack Contains :

1

Minimum Pack Size :

1

In Stock

In Stock

-1+

Product Specifications

Colorwhite
Shelf Life5 Years
PoisonousNo
EINECS No615-013-4
SmellNo Smell
StorageRoom Temperature
TasteBitter
Structural FormulaBrimonidine Base: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine Tartrate Salt: (2R,3R)-2,3-dihydroxybutanedioic acid
Ph LevelThe pH level of Brimonidine Tartrate formulations can vary depending on the specific product and its intended use. Here are some general ranges: For Eye Drop Formulations: The pH is typically adjusted to be close to 7.0 (neutral), often ranging from 4.5 to 6.5, to be compatible with the eye and prevent irritation. For Topical Gel: The pH might be slightly more acidic or closer to neutral, generally within the range of 4.5 to 6.0, to ensure both stability and skin compatibility. The pH is important for ensuring that the compound remains stable and non-irritating when used in pharmaceutical applications.
Molecular FormulaC15H16BrN5O6
Particle SizeThe particle size of Brimonidine Tartrate can vary depending on the formulation and manufacturer.
HS Code29333990
Boiling pointThe boiling point of Brimonidine Tartrate is not widely reported in standard references, as it tends to decompose before reaching its boiling point due to its complex chemical structure. Since it is used primarily in topical formulations and eye drops, it is typically not heated to the point where boiling would occur.
Heavy Metal (%)For Brimonidine Tartrate, as with most pharmaceutical compounds, the presence of heavy metals is typically monitored to ensure safety and compliance with pharmacological standards. The heavy metal content is generally tested and controlled according to pharmacopoeial standards (such as the USP or EP). The limit for heavy metals in pharmaceutical-grade Brimonidine Tartrate is typically set to 10 ppm (parts per million) or 10 g/g in the final product, depending on the specific regulations in place. This is done to ensure that any potential contaminants from metals like lead (Pb), arsenic (As), cadmium (Cd), or mercury (Hg) are kept well below toxic levels.
Loss on DryingThe Loss on Drying (LOD) for Brimonidine Tartrate typically refers to the amount of moisture that evaporates when the compound is dried under controlled conditions, typically at 105 C for 2 hours. For Brimonidine Tartrate, the Loss on Drying is typically in the range of: 1.0% This ensures that the compound is not overly hydrated, which could affect its stability, solubility, and shelf life.
Molecular Weight442.24 Grams (g)
Melting Point~205 C to 210 C (with decomposition)
SolubilityBrimonidine Tartrate is soluble in water and methanol, but its solubility in other solvents like ethanol and chloroform is limited. Here's a more detailed breakdown: Solubility in water: Freely soluble. Solubility in methanol: Freely soluble. Solubility in ethanol: Slightly soluble. Solubility in chloroform: Practically insoluble. Solubility in organic solvents: Low solubility in non-polar solvents. The solubility in water is especially important for its use in ophthalmic solutions and topical treatments, ensuring proper absorption and effectiveness.
Medicine NameBrimonidine Tartrate
Chemical Name5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine tartrate (1:1)
CAS No70359-46-5
TypePharmaceutical Intermediates
GradeMedicine Grade
UsageBrimonidine Tartrate is primarily used in ophthalmology and dermatology for the following purposes:1. Glaucoma and Ocular HypertensionMechanism: It is an alpha-2 adrenergic receptor agonist.Action: Reduces intraocular pressure (IOP) by decreasing aqueous humor production and increasing uveoscleral outflow.Brand names: Commonly found in products like Alphagan .2. Facial Redness in RosaceaMechanism: Causes vasoconstriction of dilated facial blood vessels.Form: Typically used as a topical gel or cream.Brand names: Examples include Mirvaso .
Purity(%)98%
AppearanceWhite to off-white crystalline powder It is usually odorless and freely soluble in water and methanol, but less soluble in non-polar solvents.
Physical FormPowder
FOB PortMumbai
Payment TermsLetter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Cash Advance (CA), Cash in Advance (CID)
Supply Ability1000 Per Day
Delivery Time7 Days
Sample AvailableYes
Sample PolicyFree samples are available
Packaging DetailsDrum/bag pack
Main Export Market(s)Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
CertificationsWE PROVIDES ALL KIND OF CERTIFICATIONS AS YOU REQUIRED
MRP188800.00 INR
Colorwhite
ReturnableNo
Mop1
Pkg Box Height60.00 cm
Packsize1
Price Typefixed
Brand NameBrimonidine Tartrate
Unit TypeKilograms/Kilograms
CurrencyINR
Pkg Box Breadth40.00 cm
Weight25.00 Kilogram
Pkg Box Length40.00 cm
GSTIN18%
Stock Quantity1005
Price160000.00 INR (Approx.)
Shipping Typeactual
Moq1
Minimum Ordered Packs1
Minimum Order Quantity1

Company Details

Change is inescapable, even in the business world. A company must adjust to the shifting trends of the market if it wants to be among the dominant forces in its industry. Shreeji Pharma International has evolved into one of the most effective companies in the pharmaceutical sector not only within the confines of the local markets but also globally by embracing change in each and every aspect of its operations.

With the aid of a team of brilliant scientists, the company effectively introduces a line of cost-effective pharmaceuticals that is made available worldwide. Because of this, it has earned a sterling reputation as a manufacturer, exporter, and trader of products like Cetirizine Dihydrochloride, Dextromethorphan Hydrobromide, Povidone Iodine, Riboflavin Sodium Phosphate, Aluminum Hydroxide, Cetrimide, Gabapentin, Iron Polysaccharide Complex, Calamine, and Benzyl Alcohol.

With potential to develop, scale up, and manage the logistics of countless APIs, chemicals, and pharmaceutical raw materials, the firm fulfils the orders of clients for aforesaid products without skimping on quality. In addition, it is due to cutting-edge marketing and sales strategies that the company recently generated an annual turnover of INR 25 Cr.

At Shreeji Pharma International, we focus on ethics over financial success. This explains why we consistently operate our business according to moral principles rather than resorting to deceiving clients and increasing revenue. We prefer to act in a way that benefits both us and our business partners. For the same reason, we adhere to fair trade policies and take every possible measure to provide customers with the finest possible service from a company that values both their needs and the needs of the community. All of this illustrates why picking us as your source for products like Aluminium Hydroxide, Benzyl Alcohol, Cetirizine Dihydrochloride, etc., can prove to be the wisest move.

Logistics Management

We have recruited a group of knowledgeable logistics professionals to decide on the appropriate shipping modes which we shortlist based on the price, distance and speed. These experts streamline all the routes to effortlessly document and track shipments, and manage billing. In addition, they compile an analytical performance report for each shipment, which they may review later and alter as necessary. This demonstrates our solid track record of completing orders for Calamine, Aluminum Hydroxide, and other products within the allotted time frame. Thanks to our extensive supply chain network and effectively managed logistics, we today are seen as a star export business that is also acknowledged by our Government.

Why Shreeji Pharma International?

As much we cherish our clients, they too prefer us to our counterparts for the reasons listed below:

  • Spot Reaction with Conventional COA: Have a query? Worry not! We are always here to answer your query within a brief time frame. In addition, we provide a copy of Typical Certificate of Analysis and a copy of example archives like M.S.D.S., on request of our clients.
  • Order Tracking at Fingertips: Proper logistics management also facilitates you to smoothly track your orders placed for Benzyl Alcohol, Cetirizine Dihydrochloride and all other products.
  • Free Tests: We provide free specimen pieces on special requests of our clients for their endorsements.

Specialization

Our business has developed a specialty in the markets of pharmaceutical fine chemicals, which is attributable to its extensive expertise and experience over the years. We frequently carry out surveys and research in the sector to improve in our area of expertise.


Quality

When deciding on a product quality plan, our quality auditors work with our research analysts to identify the variables that may influence our product quality. By doing this, we easily confirm the areas where our work process needs modification.

Additionally, everyone at our company operates under the guiding principle that quality is the responsibility of not just one but every individual working under our roof. Thus, our quality control plan starts when we choose the right cutting-edge technology, assess labour availability, and choose the best transportation and storage options. However, when it comes to maintaining a good quality rating, the aforementioned factors are the ones that are most frequently overlooked. By paying close attention to these factors as we design quality strategies, we provide products like Benzyl Alcohol, Calamine, and Cetirizine Dihydrochloride that pass all criteria for uncompromising quality set forth by our customers. We are accredited with ISO 9001:2015 certificate on this account.

Participation At Trade Expos

From research, development to marketing, our growth has always been backed by cost-effective pharmaceutical development and substantial manufacturing. This has motivated us to expand our business visibility by participating in various exhibitions held for pharmaceutical businesses globally, such as:

  • - CPHI Germany Expo
  • - CPHI Indonesia Expo
  • - CPHI South Africa Expo
  • - CPHI China 2016 Expo
  • - CPHI Turkey Expo
  • - CPHI Spain 2012 Expo
  • - CPHI Paris 2015 Expo
  • - Dubai Arab Health Expo
  • - CPHI India 2018 Expo


Fact Sheet of Shreeji Pharma International

Nature of Business

Exporter, Manufacturer, Supplier and Trader

Business Location

Vadodara, Gujarat

Partner

Mr. Nilesh Bansilal Sheth

Year of Establishment

2003

No. of Employees

10

Annual Turnover

INR 25 Crore

Certification

ISO 9001:2015

GST No.

24ABJFS0627F1ZE

IE Code

PAN No.

ABJFS0627F

Drugs & Cosmetic Act 1940

Licence No. 20B 11337 and 21B 113378

Udyam Registration Number

UDYAM-GJ-24-0002401

Registered at Pharmexcil

Registration Number:PXL/ME/VII/2513/2004-05

Business Type

Exporter, Manufacturer, Distributor, Supplier, Trading Company

Employee Count

10

Establishment

2003

Working Days

Monday To Sunday

GST NO

24ABJFS0627F1ZE

Certification

ISO -9001:2015

Related Products

Explore Related Categories

More Products From This Seller

Industry Leader

Seller Details

GST

GST - 24ABJFS0627F1ZE

Trusted SellerTrustedSeller
Super Bonanza

Vadodara, Gujarat

Seller Inquiry

Accepts only Foreign inquiries

Partner

Mr Nilesh Sheth / Mr. Tushar Kavade

Members since

15 Years

Address

311, Atlantis Heights, Sarabhai Main Road, Vadiwadi, Vadodara, Gujarat, 390007, India

brimonidine tartrate in Vadodara

Report incorrect details

Compare With Similar Products

Buyer Feedback

3

3

Price Or Price Range

160000.0 INR (Approx.)

2280.00 INR (Approx.)

100 INR (Approx.)

Minimum Order Quantity

25 Kilograms/Kilograms

25 Kilograms/Kilograms

1 Kilograms/Kilograms

Color

white

White to slightly yellowish

Other, White to off-white

Shelf Life

5 Years

5 Years

2 years (if properly stored)

Poisonous

No

Other, No (used under medical supervision)

EINECS No

615-013-4

274-584-5

274-492-2

Smell

No Smell

Other, Odorless

Storage

Room Temperature

Other, Store in a cool, dry place, protected from light

Structural Formula

Brimonidine Base: 5-Bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine Tartrate Salt: (2R,3R)-2,3-dihydroxybutanedioic acid

Brimonidine tartrate

See image

Ph Level

The pH level of Brimonidine Tartrate formulations can vary depending on the specific product and its intended use. Here are some general ranges: For Eye Drop Formulations: The pH is typically adjusted to be close to 7.0 (neutral), often ranging from 4.5 to 6.5, to be compatible with the eye and prevent irritation. For Topical Gel: The pH might be slightly more acidic or closer to neutral, generally within the range of 4.5 to 6.0, to ensure both stability and skin compatibility. The pH is important for ensuring that the compound remains stable and non-irritating when used in pharmaceutical applications.

As per COA

4.5 - 6.5 (1% aq. solution)

Molecular Formula

C15H16BrN5O6

C H BrN O

C11H10BrN5C4H6O6

Particle Size

The particle size of Brimonidine Tartrate can vary depending on the formulation and manufacturer.

As per COA

Micronized (as per requirement)

HS Code

29333990

29335990

29339900

Boiling Point

The boiling point of Brimonidine Tartrate is not widely reported in standard references, as it tends to decompose before reaching its boiling point due to its complex chemical structure. Since it is used primarily in topical formulations and eye drops, it is typically not heated to the point where boiling would occur.

Not applicable

Not applicable (decomposes before boiling)

Heavy Metal (%)

For Brimonidine Tartrate, as with most pharmaceutical compounds, the presence of heavy metals is typically monitored to ensure safety and compliance with pharmacological standards. The heavy metal content is generally tested and controlled according to pharmacopoeial standards (such as the USP or EP). The limit for heavy metals in pharmaceutical-grade Brimonidine Tartrate is typically set to 10 ppm (parts per million) or 10 g/g in the final product, depending on the specific regulations in place. This is done to ensure that any potential contaminants from metals like lead (Pb), arsenic (As), cadmium (Cd), or mercury (Hg) are kept well below toxic levels.

As per COA

Not more than 0.001%

Loss On Drying

The Loss on Drying (LOD) for Brimonidine Tartrate typically refers to the amount of moisture that evaporates when the compound is dried under controlled conditions, typically at 105 C for 2 hours. For Brimonidine Tartrate, the Loss on Drying is typically in the range of: 1.0% This ensures that the compound is not overly hydrated, which could affect its stability, solubility, and shelf life.

NMT 1.0%*

Not more than 0.5%

Molecular Weight

442.24 Grams (g)

442.22 g GSM (gm/2)

442.2 g/mol

Melting Point

~205 C to 210 C (with decomposition)

205 C~210 C

220-225C (decomposes)

Solubility

Brimonidine Tartrate is soluble in water and methanol, but its solubility in other solvents like ethanol and chloroform is limited. Here's a more detailed breakdown: Solubility in water: Freely soluble. Solubility in methanol: Freely soluble. Solubility in ethanol: Slightly soluble. Solubility in chloroform: Practically insoluble. Solubility in organic solvents: Low solubility in non-polar solvents. The solubility in water is especially important for its use in ophthalmic solutions and topical treatments, ensuring proper absorption and effectiveness.

Soluble in water; slightly soluble in alcohol

Soluble in water, slightly soluble in methanol and ethanol

Medicine Name

Brimonidine Tartrate

Brimonidine

Brimonidine Tartrate

Chemical Name

5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine tartrate (1:1)

5-Bromo-6-(2-imidazolidinylideneamino)quinoxaline L-tartrate

5-Bromo-6-(2-imidazolidinylideneamino)quinoxaline tartrate

CAS No

70359-46-5

70359-46-5

70359-46-5

Type

Pharmaceutical Intermediates

Pharmaceutical Intermediates

Other

Grade

Medicine Grade

Medicine Grade

Other

Usage

Brimonidine Tartrate is primarily used in ophthalmology and dermatology for the following purposes:1. Glaucoma and Ocular HypertensionMechanism: It is an alpha-2 adrenergic receptor agonist.Action: Reduces intraocular pressure (IOP) by decreasing aqueous humor production and increasing uveoscleral outflow.Brand names: Commonly found in products like Alphagan .2. Facial Redness in RosaceaMechanism: Causes vasoconstriction of dilated facial blood vessels.Form: Typically used as a topical gel or cream.Brand names: Examples include Mirvaso .

Selective -adrenergic receptor agonist; used in ophthalmic preparations for glaucoma and ocular hypertension

Treatment of open-angle glaucoma or ocular hypertension

Purity(%)

98%

99

99%

Appearance

White to off-white crystalline powder It is usually odorless and freely soluble in water and methanol, but less soluble in non-polar solvents.

White to slightly yellowish powder

White to off-white powder

Physical Form

Powder

Powder

Solid

FOB Port

Mumbai

MUMBAI

Payment Terms

Letter of Credit at Sight (Sight L/C), Letter of Credit (L/C), Cash Advance (CA), Cash in Advance (CID)

Western Union, Others, Cash Advance (CA), Paypal, Cash on Delivery (COD)

Supply Ability

1000 Per Day

300 Per Week

2000 Per Day

Delivery Time

7 Days

15 Days

1 Days

Packaging Details

Drum/bag pack

25kg/drum with double plastic bags inside; packed in a cardboard drum or fiber HDPE drum.

Main Export Market(s)

Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa

Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa