Bam 15 Api Intermediate - Cas No: 210302-17-3

10000.0 INR (Approx.)

1300 INR (Approx.)

2 Years

2 years under proper storage conditions

Freezer

Store in a cool dry and well-ventilated area away from incompatible materials, Other

2-fluorophenyl {6-(2-fluorophenyl)amino}amine)

2-Bromo-5-Methyl Pyridine

Pharmaceutical Intermediates

Other, Chemical Compound

BAM-15 (scientific name: 2-fluorophenyl {6-(2-fluorophenyl)amino}amine) is a chemically synthesized compound that functions as a mitochondrial uncoupler. To understand its action, one must first understand the process of oxidative phosphorylation. In normal cellular respiration, the electron transport chain (ETC) pumps protons across the mitochondrial inner membrane, creating a proton gradient. This gradient drives the enzyme ATP synthase to produce adenosine triphosphate (ATP), the cell's primary energy currency. Mitochondrial uncouplers, like BAM-15, disrupt this process by shuttling protons back across the membrane, bypassing ATP synthase. This "short-circuit" dissipates the proton gradient as heat, thereby reducing the efficiency of ATP production. Consequently, the cell must increase its metabolic rate and oxidize more substrates (including fats and glucose) to meet its energy demands. Unlike earlier uncouplers such as 2,4-dinitrophenol (DNP), which was effective but notoriously toxic, BAM-15 has been specifically engineered for a superior safety profile, demonstrating high selectivity for the mitochondrial membrane without disrupting its integrity.

Intermediate in chemical synthesis and manufacturing

Powder

Liquid

Powder

10 Days

14 Days

Pale yellow, Other

White

Colorless to pale yellow liquid

white to off white crystalline powder