Azd-9291
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Product Specifications
| CAS Number | 1234567-89-0 |
| Molecular Formula | C23H26N6O2 |
| Molecular Weight | 418.48 g/mol |
| Purity | 99% |
| IC50 (Exon 19) | 12.92 nM |
| IC50 (L858R/T790M) | 11.44 nM |
| Usage | Advanced lung cancer treatment; Inhibits EGFR mutations |
| Features | EGFR inhibitor, Cancer treatment, Targeted therapy, Reduced side effects |
Product Overview
Key Features
IC50 value: 12.92 nM(Exon 19 deletion EGFR); 11.44 nM(L858R/T790M EGFR) [1]
Target: L858R/T790M EGFR; Exon 19 deletion EGFR
AZD-9291 is a third-generation EGFR inhibitor, showed promise in preclinical studies and provides hope for patients with advanced lung cancers that have become resistant to existing EGFR inhibitors. It inhibits both activating and resistant EGFR mutations while sparing the normal form of EGFR that is present in normal skin and gut cells, thereby reducing the side effects encountered with currently available medicines.
Patent: WO
Company Details
Focusing on a customer-centric approach, ZHEJIANG ESUN CHEMICAL CO., LTD. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Raw Materials & Ingredients in bulk from ZHEJIANG ESUN CHEMICAL CO., LTD. at Trade India quality-assured products.
Business Type
Exporter, Manufacturer
Employee Count
80
Establishment
2001
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Seller Details
Hangzhou, Zhejiang
Manager
Mr. Zhang
Address
Sales Office: No.29 Qingchun Rd., Shangcheng Area, Hangzhou, Zhejiang, 310030, China
api intermediate in Hangzhou
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