Alkacel 50mg Injection - Melphalan Lyophilized Powder, Intravenous Infusion | Cancer Treatment, High-dose Therapy, Palliative Use

By keeping track with the market developments, we are eminent Trader, Exporter, Distributor and Supplier of Alkacel 50Mg Injection in Kurnool, Andhra Pradesh, India. Alkacel 50Mg Injection is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents.
An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring.
Otherwise known as L-phenylalanine mustard, or L-PAM, melphalan is a phenylalanine derivative of mechlorethamine.
It is used to treat multiple myeloma, ovarian cancer, AL amyloidosis, and occasionally malignant melanoma.
The agent was first investigated as a possible drug for use in melanoma, it was not found to be effective.
On March 15, 2016 it was approved by the U.S. FDA under the trade name Evomela for:
use as a high-dose conditioning treatment prior to hematopoietic progenitor (stem) cell transplantation in multiple myeloma (MM) patients
the palliative treatment of MM patients for whom oral therapy is not appropriate
Melphalan is currently being used to treat ocular retinoblastoma, a pediatric solid tumor. This is accomplished via transarterial catheter based slow pulsed infusion into the ophthalmic artery.