Acadesine - C9h14n4o5 | Treats Tumors, Protects Against Cardiac Ischemia, Stimulates Ampk Activity

Acadesine
Formula: C9H14N4O5
Synonyms: Imidazole-4-carboxamide,5-amino-1-b-D-ribofuranosyl- (6CI,7CI,8CI);1-Ribosyl-4-carboxamido-5-aminoimidazole;1-b-D-Ribofuranosyl-5-amino-4-imidazolecarboxamide;5-Amino-1-ribosyl-4-imidazolecarboxamide;5-Amino-1-b-D-ribofuranosylimidazol
Molecular Weight: 258.23
CAS No.: 2627-69-2
Melting Point: 214-215 A C
Applicatoion: AICAR acts by entering nucleoside pools,significantly increasing level of adenosine during periods of ATP breakdown.
Function:Acadesine/Aicar is used to treat tumours.
AICAR also known as ZMP is an analog of AMP that is capable of stimulating AMP-dependent protein kinase activity (AMPK). AICAR is being clinically used to treat and protect against cardiac ischemic injury. If left untreated, it may lead to a myocardial infarct. Cardiac Ischemia is caused by insufficient blood flow and oxygen to the myocardium .The drug was first used in the 1980a s as a method to preserve blood flow to the heart during surgery. Currently, the drug has also been shown as a potential treatment for diabetes by increasing the metabolic activity of tissues by changing the physical composition of muscle.