Artemether
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Artemether is amedicine used to treat malaria. Rather than quinine, the injectable version is
used for severe malaria. It may not be as effective in adults as artesunate. In
the muscles, it is given as an injection. Artemether/lumefantrine is also
available by mouth in conjunction with lumefantrine. Artemether is a methyl
ether compound of artemisinin, a peroxide-containing lactone discovered from
the antimalarial herb Artemisia annua.
Dihydroartemisinin methyl ether is another name of artemether. It is a
somewhat lipophilic and unstable medication that functions by generating
reactive free radicals as well as harming the plasmodium organism's membrane
transport mechanism.
Artemether is an
artemisinin derivative, and artemisinins' is the mode of action. Artemether
reacts with ferriprotoporphyrin IX (heme) or ferrous ions in the acidic
parasite feeding vacuole and causing cytotoxic radical species. The
peroxide-containing drug's acknowledged method of action involves its
interaction with heme (a result of hemoglobin breakdown), which is produced
from hemoglobin proteolysis. As a result of this interaction, harmful oxygen
and carbon-centered radicals are formed.
Warnings for Taking Artemether:
- Pregnancy: Pregnant women should not use this medication unless absolutely essential. Because the impact of this treatment on pregnancy is unknown, it should be taken only in life-threatening conditions.
- Breast-feeding: It is not suggested to use this medication during nursing unless absolutely essential. Your doctor will decide whether or not you should take this medication.
- Severe malaria: This antibiotic should only be used to treat malaria when other treatments, such as quinine, have proven unsuccessful.
- Liver/kidney impairment: In individuals with compromised liver/kidney function, this medication should be taken with care. If the impairment is severe, it is best to avoid using this medication.
- Heart disease: This medication should be taken with caution in people who have a pre-existing cardiac issue. In such circumstances, appropriate dosage modifications and periodic clinical monitoring are advised.
- Drug resistance: Even if symptoms subside or improve, it is strongly advised to continue taking this medication for the full term specified. Failure to do so may result in parasite resistance to the therapy, making treatment of subsequent infections with this medicine difficult.
Interested buyers may check out the available generic medicine, Artemether for their local business needs. The sellers listed at Tradeindia deal in different brands of this medicine. Buyers can examine the details of each product and choose according to their satisfaction. We assure them that they will get the best products here at market leading prices.
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This Data was Last Updated on 2023-12-09
Artemether Manufacturers | Suppliers in India
Company Name | Location | Member Since |
---|---|---|
Medico Remedies Ltd | Mumbai, India | 17 Years |
Jai Radhe Sales | Ahmedabad, India | 16 Years |
Schwitz Biotech | Ahmedabad, India | 16 Years |
Devlife Corporation Private Limited | Mumbai, India | 13 Years |
Aaditya Pharmachem | Mumbai, India | 12 Years |
Lexicare Pharma Pvt. Ltd. | Ankleshwar, India | 11 Years |
Niksan Pharmaceutical | Ankleshwar, India | 10 Years |
Prism Industries Private Limited | Anand, India | 10 Years |
Salvavidas Pharmaceutical Pvt. Ltd. | Surat, India | 9 Years |
Johnlee Pharmaceuticals Pvt. Ltd. | Mumbai, India | 9 Years |
FAQs Related to Artemether
Artemether is an
antimalarial medication used to treat acute uncomplicated malaria. It is used
in conjunction with lumefantrine to increase effectiveness. This combination
medication works against the erythrocytic stages of Plasmodium spp. and would
be used to treat infections caused by malaria.
Rather than
quinine, the injectable version is used for severe malaria. It may be less
effective than artesunate. In muscles, it is given as an injection.
Artemether/lumefantrine is also available by mouth in conjunction with
lumefantrine. Artemether has a low number of adverse effects.
Its primary
component is artemether, a very potent anti-malarial that has been demonstrated
to reduce fever in as little as 32-48 hours. It comes as a solution for
injections, which should only be delivered by your doctor or healthcare
practitioner into a major muscle.
Artemether is
converted in the body to the active metabolite dihydroartemisinin. By
suppressing nucleic acid and protein synthesis, the medication works against the
erythrocytic stages of P. falciparum. Artemether is used in conjunction with
lumefantrine to increase effectiveness.
The medicine
operates against the erythrocytic stages of P. falciparum by suppressing nucleic
acid and protein production. Artemether is used in conjunction with
lumefantrine to increase effectiveness. Artemether has a rapid beginning of
effect and is quickly eliminated from the body.
The chemical formula
of artemether is C16H26O5.
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