Tamsulosin Ip/bp/usp/ep Cas No: 106133-20-4

Niksan Pharmaceutical is the largest manufacturer and exporter of the Tamsulosin among all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributer of the Tamsulosin API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.
Niksan Pharmaceutical provides API and finished formulations of Tamsulosin in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.
Niksan pharmaceutical is also large exporters of the API and finished pharmaceutical products of Tamsulosin in many countries for years. The countries where we exporting are Puerto Rico, United States, Ghana, Canada, Germany, Philippines, United Kingdom, Pakistan, Ireland, Nigeria, Switzerland, Sri Lanka, Austria, United Arab Emirates, Slovakia, Singapore, Kenya, Bangladesh, Australia, Iraq, India, New Zealand, Taiwan, Norway, Egypt, Hong Kong, Saudi Arabia, Hungary, Malaysia, Israel, Romania, Czechia, South Korea, Iran, Denmark, South Africa, Italy, Indonesia, Greece, Finland, Thailand, Vietnam, Colombia, Belgium, Netherlands, Turkey, Mexico, Spain, Poland, France, Brazil and many more countries.
Tamsulosin comes under the alpha-blocker medicine. Tamsulosin relax the muscles of bladder and by this the urine can flow easily.
Tamsulosin used in the treatment of enlarged prostate (BPH) (benign prostatic hyperplasia) in male.
SYNONYMS: Tamsulosin, Tamsulosina, Tamsulosine, Tamsulosinum.
IUPAC NAME: (R)-5-(2-{[2-(2-Ethoxyphenoxy) ethyl] amino} propyl)-2-methoxybenzene-1-sulfonamide
CAS NO: 106133-20-4
FORMULA: C20H28N2O5S
MOLECULAR MASS: 408.5117 g/mol
STORAGE CONDITION: Store in room temperature in dry place. Put it away of light and direct heat. Do not put it in bathroom or in kitchen.

HOW TO USE: Kindly read the instruction given on the label and ask doctor for the advice. Take medication once a 30 min before the meal. Do not open, crush or chew the capsule. Take medication regularly to improve the effects.

HOW TAMSULOSIN WORKS: Tamsulosin blocks the alpha A1 and alpha 1D receptors.
By blocking the receptor the smooth muscles of kidney and bladder relaxes and by this the urinary flow improved and also prevents the storage process of bladder.

PHARMACOKINETICS OF TAMSULOSIN: Tamsulosin blocks the alpha A1 and alpha 1D receptors and relaxes the smooth muscles. The half-life of Tamsulosin is 9-13 hours.
Approximately 94-99% of Tamsulosin binds with the plasma protein. 76% of drug is eliminated by the urination and the remaining drug eliminated in feces.

SIDE EFFECT OF TAMSULOSIN: The side effects of Tamsulosin are runny nose, drowsiness, ejaculation problem. If you find some serious side effect like fainting, abdominal pain, pain in kidney or breathing problem contact you doctor.

PRECAUTION: Tell your doctor if you have problems like low blood pressure, glaucoma and some eye problems. If you have allergy from Tamsulosin, kindly take alternative medication. Tamsulosin cause low blood pressure and also cause fainting which increases the risk of falling. So kindly take care about it. Do not do any exercise or heavy lifting.

CDSCO APPROVAL: Tamsulosin + Finasteride approved by CDSCO in India in19.03.2004,
Tamsulosin + Tolterodine (0.4mg MR Pellets + 2mg/4mg ER Pellets) Capsules approved by CDSCO in India in 17.11.2008,
Combikit of Tamsulosin HCl 0.4mg M.R capsules (10 no.) & Dutasteride Soft Gelatine Capsule 0.5mg (10no.) approved by CDSCO in India in 19.01.2006,
Tamsulosin HCl MR Capsules approved by CDSCO in India in 04.04.2002,
Tamsulosin HCl (MR) 0.4mg + Dutasteride 0.5mg tablets approved by CDSCO in India in 06.02.2006,
Tolterodine Tartrate 4mg (ER) + Tamsulosin HCL 0.4mg Capsules approved by CDSCO in India in 15.06.2007.

FORMULATIONS AVAILABLE IN MARKET:
Tamsulosin 0.2mg pellets
Tamsulosin 0.4 mg pellets
Tamsulosin + Finasteride capsules
Tamsulosin 0.4mg + Tolterodine 2mg pellets
Tamsulosin 0.4mg + Tolterodine4mg pellets
Tamsulosin HCl 0.4mg M.R &Dutasteride Soft Gelatine Capsule 0.5mg
Tamsulosin HCl (MR) 0.4mg + Dutasteride 0.5mg tablets
Tolterodine Tartrate 4mg (ER) + Tamsulosin HCL 0.4mg Capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult