IMOVAX PolioInactivated Poliomyelitis Vaccine (Vero Cell Origin)DESCRIPTIONIMOVAX Polio [Inactivated Poliomyelitis Vaccine (Vero Cell Origin)] is a sterile suspension ofthree types of poliovirus: Type 1 (Mahoney), Type 2 (MEF1) and Type 3 (Saukett). This vaccineis prepared from types 1, 2 and 3 of poliomyelitis virus cultured on Vero cells, purified and theninactivated by formaldehyde.INDICATIONS & CLINICAL USEIMOVAX Polio [Inactivated Poliomyelitis Vaccine (Vero Cell Origin)] is indicated for activeimmunization against poliomyelitis caused by poliovirus types 1, 2 and 3 in infants, children andadults both for primary immunization and for boosters. Children Incompletely ImmunizedChildren of all ages should have their immunization status reviewed and be considered forsupplemental immunization.AdultsAll adults at risk of exposure to poliovirus should have their immunization status reviewed. Forthose who are unvaccinated, who have a history of incomplete immunization, or for whomimmunization is uncertain, a primary series of IMOVAX Polio is recommended. The following categories of persons are at increased risk ofexposure to poliovirus: (1) (3) travellers to areas of countries where poliomyelitis is still transmitted (4) or may be a risk; (5) laboratory workers handling specimens that may contain polioviruses; health-care workers in close contact with persons who may be excreting wild or vaccinestrains of polioviruses; unimmunized parents or child-care workers who will be caring for children or unimmunizedadults who may be in contact with children (6) in countries where OPV is used, (1) or in rareinstances in which infants receive OPV in a country in which inactivated poliomyelitisvaccine (IPV) is normally used. members of communities or specific population groups with disease caused by wildpoliovirus. (7)IMOVAX Polio can be used for completing immunization series in cases of previous clinicalpoliomyelitis (usually due to only a single poliovirus type) or incomplete immunization withOPV.PediatricsSafety and efficacy of IMOVAX Polio have been shown in children 6 weeks of age and older.CONTRAINDICATIONSImmunization with IMOVAX Polio [Inactivated Poliomyelitis Vaccine (Vero Cell Origin)]should be deferred in the presence of any acute illness, including febrile illness, to avoidsuperimposing adverse effects from the vaccine on the underlying illness or mistakenlyidentifying a manifestation of the underlying illness as a complication of vaccine use. A minorillness such as mild upper respiratory infection is not reason to defer immunization. (1)Allergy to any component of IMOVAX Polio [Inactivated Poliomyelitis Vaccine (Vero CellOrigin)], or its container, or an anaphylactic or other allergic reaction to a previous dose ofIMOVAX Polio is a contraindication to vaccination. For a complete listing, see the DOSAGEFORMS, COMPOSITION AND PACKAGING section of the product monograph.
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