Terbinafine Ip/bp/usp/ep Cas No: 91161-71-6

Niksan Pharmaceutical and the Niksan group companies are the worlda s top most leading pharmaceutical companies in the exporting, supplying and manufacturing Terbinafine API and also the finished pharmaceutical products of Terbinafine like Terbinafine tablets and Terbinafine formulations. Niksan Pharmaceuticala s Terbinafine product is appreciated widely by our group companies and by the customers all around the world.

Niksan Pharmaceutical is one of the most leading distributor, supplier, exporter and manufacturer of Terbinafine products.

Niksan Pharmaceutical provides Terbinafine API in all over Indian states like Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Haryana, Telangana, Bihar, Karnataka, Kerala, Punjab, Rajasthan, Andhra Pradesh in huge quantity.

Niksan pharmaceutical also manufacturing, trading, supplying and exporting Terbinafine API and Finished formulations in countries of Nepal, Jamaica, Trinidad & Tobago, Tanzania, Netherlands, New Zealand, Kenya, UK, USA, Puerto Rico, Hong Kong, Pakistan, Belgium, Nigeria, Lebanon, Bangladesh, Tunisia, Canada, Australia, Latvia, Morocco, UAE, Algeria, Ireland, France, Israel, Philippines, Taiwan etc.

Terbinafine is an anti-fungal medicine that fights again fungus.
Terbinafine is used to many fungal infections like fungal nail infections, ringworm, and pityriasis versicolor.
Terbinafine is an ally amine derivative which is take action against dermatophytosis and other filamentous fungi.

SYNONYMS: Terbinafina, Terbinafine, Terbinafinum

IUPAC NAME: [(2E)-6, 6-dimethylhept-2-en-4-yn-1-yl](methyl)[(naphthalen-1-yl)methyl]amine

CAS NO: 91161-71-6

FORMULA: C21H25N

MOLECULAR MASS: 291.43 g/mol

STORAGE OF TERBINAFINE: Store it in cool& dry place. Terbinafine is light sensitive drug so keep away from light and also put it in the light resistance container.

APPLICATIONS OF TERBINAFINE: Terbinafine is used to treatment of fingernail or toenail fungal infection. This medicine stopping the growth of fungus so this drug belongs to class of antifungal.

HOW TO USE: Apply the Terbinafine solution in enough amounts to cover the affected skin areas. Do not contact this medicine with nose, eyes, mouth, and other mucous membrane. Take this tablet once daily for 6 weeks to protection against fingernail infection and 12 weeks to protection against toenail infection.

HOW TERBINAFINE WORKS: Terbinafine kills fungal cells. It makes holes in the cell membrane of fungal cells and by that it will treats the fungal infection.

CONTRAINDICATIONS OF TERBINAFINE: Kindly avoid Terbinafine if you have chronic or active liver disease. Do not take this medicine if you have allergic to Terbinafine in your past history.

PHARMACOKINETICS OF TERBINAFINE: 70% Terbinafine is absorbed by oral administration. Half-life of Terbinafine is 36 hours. Peak Plasma Concentration of Terbinafine is 25%. 80% Terbinafine excreted by urine.

SIDE EFFECTS OF TERBINAFINE: Most common side effect of Terbinafine is Gastrointestinal problems like diarrhoea, dyspepsia, gastritis, cholestasis, flatulence, altered stool colour, constipation, nausea, fullness, abdominal pain, indigestion, abdominal muscular pain etc. Other side effects are observed like headache, dizziness, vertigo and more skin problem like rashes, skin irritation, itching etc. Sometimes this medicine cause Psychological problems like depression, anxiety, insomnia, increased or unusual dream activity and malaise.

PRECAUTIONS: Before using the medication of Terbinafine share your medical history with your doctor or pharmacist. Dry your body properly after bathing if you use tube of Terbinafine for ringworm. Stop taking this medicine if the infection or skin irritation is increase. Avoid too much heat and humidity if possible.

CDSCO APPROVAL: Terbinafine tab/cream approved by CDSCO in India in 29.03.1995
Mometasone furoate + Terbinafine HCl cream approved by CDSCO in India in 16.01.2002

FORMULATION AVAILABLE IN MARKET:
Terbinafine tablets
Terbinafine cream
Terbinafine 1 %W/W cream
Terbinafine 1 %W/V cream
Terbinafine 250 MG tablet s
Terbinafine 500 MG tablet s
Itraconazole 1 %W/W +Terbinafine 1 %W/W cream
Luliconazole 1 %W/W +Terbinafine 1 %W/W cream
Beclometasone 0.025 %W/W +Terbinafine 1 %W/W cream
Salicylic Acid 3 %W/W +Terbinafine 1 %W/W cream
Clobetasol propionate 0.05 %W/W+ Terbinafine 1 %W/W cream
Itraconazole 100 MG +Terbinafine 250 MG tablets
Mometasone furoate 0.1 %W/W +Terbinafine 1 %W/W cream
Mometasone Furoate 0.1 %W/V +Terbinafine 1 %W/V gel
Mometasone furoate + Terbinafine HCl cream

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult