Fatty Acid Ethoxylate By Gujarat Chemicals

Physical and Analytical Data
STEARIC ACID ETHOXYLATE (SEA)


GUJCHEM
APPEARANCE AT 25 c
SAPO-
NIFICATION VALUE
IODINE VALUE
HLB
ACID VALUE
MOLECULAR WEIGHT
MELTING POINT


SEA-5.0
Soft solid
1115
1.0
8.89
111-117

505
28


SEA-6.5
Soft solid
1005
1.0
9.7
99-105
570
28


SEA-8
Waxy cream
895
1.0
11.1
89-95
637
30


SEA-10
Pasty solid
785
1.0
12.6
83-87
725
31


SEA-12
Pasty solid
705
1.0
13.00
67-73
813
32


SEA-20
Waxy solid
615
1.0
15.12
46-52
1165
34


SEA-30
Waxy solid
535
1.0
16.46
32-38
1605
36


SEA-40
Waxy solid with a faint, bland, fat like odor, off white to light tan in color
425
1.0
17.22
24-30
2046
38


SEA-50
Solid with a bland, fat like odor or odorless
355
1.0
17.71
19-25
2486
42


LAURIC ACID ETHOXYLATE (LEA)


GUJCHEM
APPEARANCE AT 25 c
SAPO-
NIFICATION VALUE
IODINE VALUE
HLB
MOLECULAR WEIGHT
PH


LEA-5.0
Soft solid viscous
1355
0.5
10.48

420
6.00-8.00


LEA-6.5
Soft solid viscous
1175
0.5
11.77
486
6.00-8.00


LEA-8.0
Clear liquid
1035
0.5
12.75
552
6.00-8.00


LEA-10
Clear liquid
895
0.5
13.75
640
6.00-8.00


LEA-15
Pasty liquid
665
0.1
15.35
861
6.00-8.00


LEA-20
Waxy solid
525
0.1
16.30
1081
6.00-8.00


LEA-30
Waxy solid
375
0.1
17.37
1521
6.00-8.00


LEA-40
Waxy solid
295
0.1
17.96
1962
6.00-8.00


OLEIC ACID ETHOXYLATE (OEA)


GUJCHEM
SAPO-
NIFICATION VALUE
IODINE VALUE
HLB
ACID VALUE
MOLECULAR WEIGHT
PH


OEA-5.0
1115
52-57
8.89
111-113

502
6.00-8.00


OEA-6.5
995
47-52
10.10
99-102
568
6.00-8.00


OEA-8
895
42-47
11.11
89-91
634
6.00-8.00


OEA-10
785
37-41
12.19
78-80
723
6.00-8.00


OEA-15
615
28-31
14.01
59-61
943
6.00-8.00


OEA-20
495
23-26
15.15
48-50
1163
6.00-8.00


OEA-30
355
17-20
16.49
35-37
1603
6.00-8.00


OEA-40
285
13-15
17.24
27-29
2045
6.00-8.00


MYRISTIC ACID ETHOXYLATE (MEA)


GUJCHEM
SAPO-
NIFICATION VALUE
PH VALUE
HLB
MOISTURE CONTENT MAX.
MOLECULAR WEIGHT


MEA-5.0
1015
6.00-8.00
9.85
1.0

449


MEA-6.5
885
6.00-8.00
11.11
1.0
515


MEA-8
785
6.00-8.00
12.16
1.0
581


MEA-10
685
6.00-8.00
13.17
1.0
669


MEA-15
645
6.00-8.00
14.87
1.0
889


MEA-20
615
6.00-8.00
15.88
1.0
1110


MEA-30
445
6.00-8.00
17.05
1.0
1550


COCONUT FATTY ACID ETHOXYLATE (CEA)


GUJCHEM
SAPO-
NIFICATION VALUE
PH VALUE
HLB
MOISTURE CONTENT MAX.
MOLECULAR WEIGHT
IODINE VALUE


CEA-5.0
1345
6.00-8.00
10.02
1

435
51


CEA-6.5
1175
6.00-8.00
11.50
1
501
51


CEA-8.0
1035
6.00-8.00
12.50
1
567
41


CEA-10
895
6.00-8.00
13.50
1
655
31


CEA-15
675
6.00-8.00
15.00
1
875
31


CEA-20
545
6.00-8.00
16.00
1
1095
21


CEA-30
385
6.00-8.00
17.00
1
1535
11


CEA-40
305
6.00-8.00
19.05
1
1975
11


Functional CategoryEmulsifying agent; solubilizing agent; wetting agent.
APPLICATIONS IN PHARMACEUTICAL FORMULATION OR TECHNOLOGY
GUJCHEM-SEA
are generally used as emulsifiers in oil-in-water type creams and
lotions. Their hydrophilicity or lipophilicity depends on the number of
ethylene oxide units present; the larger the number, the greater the
hydrophilic properties. GUJCHEM-SEA-40 has also been used as an
emulsifying agent in intravenous infusions.
GUJCHEM-SEA are particularly useful as emulsifying agents when astringent salts or other strong electrolytes are present.
They
can also be blended with other surfactants to obtain any
hydrophilic-lipophilic balance for lotions or ointment formulations.


Use
Concentration


Auxiliary emulsifier for o/w intravenous fat emulsion
0.5-5


Emulsifier for o/w creams or lotions
0.5-10


Ophthalmic ointment
7


Suppository component
1-10


Tablet lubricant
1-2


SOLUBILITY


Name
Solvent Ethanol (95%)
Mineral Oil
Water


GUJCHEM SEA-6
S
S
DH


GUJCHEM SEA-8
S
I
D


GUJCHEM SEA-12
S
I
S


GUJCHEM SEA-20
S
I
S


GUJCHEM SEA-40
S
I
S


GUJCHEM SEA-50
S
I
S


Where
D = Dispersible, S = Soluble, I = Insoluble and DH = Dispersible (with Heat)
STABILITY AND STORAGE
GUJCHEM-SEA
are generally stable in the presence of electrolytes and weak acids or
bases. Strong acids and bases can cause gradual hydrolysis and
saponification.
The bulk material should be stored in a well-closed container, in a dry place, at room temperature.
INCOMPATIBILITIES
GUJCHEM-SEA
are unstable in hot alkaline solutions due to hydrolysis, and will also
saponify with strong acids or bases. Discoloration or precipitation can
occur with salicylates, phenolic substances, iodine salts and salts of
bismuth, silver and tannins. Complex formation with preservatives may
also occur.
The
antimicorbial activity of some materials such as bacitracin,
chloramphenicol, phenoxymethylpenicillin, sodium penicillin and
tetracycline may be, reduced in the presence of GUJCHEM-SEA
concentrations greater than 5% w/w.
SAFETY
Although
GUJCHEM-SEA are primarily used as emulsifying agents in topical
pharmaceutical formulations certain materials, particularly
GUJCHEM-SEA-40 have also been used intravenous injections and oral
preparations.
GUJCHEM-SEA
have been extensively tested for toxicity in animals and are widely
used in pharmaceutical formulations and cosmetics. They are generally
regarded as essentially nontoxic and nonirritant materials.
HANDLING PRECAUTIONS
Observe normal precautions appropriate to the circumstances and quantity of material handled.
GUJCHEM-SEA
that contain greater than 100 ppm of free ethylene oxide may present an
explosion hazard when stored in a closed container. This is due to the
release of ethylene oxide into the container headspace where it can
accumulate, and so exceed the explosion limit.


Note: Above
Gujchem Range are the running products. We can produce higher moles
on customer specific demand and specifications can be altered as per
customer requirement.