Medicine Raw Materials Cilnidipine Ip/bp/usp

Niksan Pharmaceutical is one of the leading Manufacturer, Exporter, Distributor, and Supplier of Cilnidipine in Ankleshwar, Gujarat, India. To understand the largest accomplishment of clients, we present these products at very realistic price ranges. Niksan Pharmaceutical and Niksan group companies are nowadays one of the largest manufacturers and exporters of Cilnidipine API and also finished formulations.

Niksan Pharmaceutical provides Cilnidipine to all states of India like Punjab, Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka, Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, and Madhya Pradesh etc. We also give gift samples to the companies for R&D purpose.

Niksan Pharmaceutical is also an exporter of Cilnidipine. We export our API and formulations to many countries like Myanmar (Burma), Bangladesh, Sri Lanka, United Arab Emirates, Kenya, Vietnam, Saudi Arabia, Australia, United States, United Kingdom, Japan, Myanmar, Shrilanka, UAE, Kenya, Vietnam, Australia, Saudi Arabia, United States, United Kingdom, China, and Korea and also in some European countries.

Cilnidipine comes under the calcium channel blocker class of medicine. Most of it is used as anti-hypertensive agent. Cilnidipine have compatibility with other API like Telmisartan, Olmesartan Medoxomil, Ramipril and Metoprolol Succinate. Cilnidipine can act on the N-type calcium channel in addition to acting on the L-type calcium channel. Cilnidipine dilates both arterioles and venules, reducing the pressure in the capillary bed.

IUPAC NAME: 3-(2-methoxyethyl) 5-(2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

CAS NO: 132203-70-4

FORMULA: C27H28N2O7

MOLECULAR MASS: 492.52 g/mol

STORAGE: Store the medicine in cool and dry place. Store it away from the direct sun light. Do not change packet of the Cilnidipine tablet. Keep away from reach of children and pets.

APPLICATION: Cilnidipine is primarily used for the treatment of high blood pressure also referred to as hypertension. The Cilnidipine have the calcium channel blocker activity it is also used in the treatment of headache, vision related problems, irregular heartbeat, chest pain, and fatigue.

HOW TO USE: Simply take the medicine as per your doctor says. The tablet should be taken orally with water. The tablet must be swallowed whole without breaking or chewing.

HOW CILNIDIPINE WORKS: Cilnidipine blocks the calcium channels in blood vessels. By this the blood supplies towards the heart increase and by that the hypertension decreases.

CONTRAINDICATIONS: Do not take Cilnidipine medicine in pregnancy and lactation period. Do not give medicine to the patient under 18 years. If you have any confusion related to the medicine consult to your doctor.

PHARMACOKINETICS: Cilnidipine is one type of lipophilic drug. So mainly it is metabolites in the liver or kidneys. Cilnidipine is rapidly absorbed in the blood plasma in only 2hrs.Cilnidipine normally excreted by urination.

SIDE EFFECTS: There are some common side effects of the Cilnidipine are Dizziness, hypotension, swelling of (face, eyes, tongue, and feet), fast heartbeats, muscle pain, stomach pain, skin rash.

PRECAUTIONS: Dona t take medicine if you are allergic to Cilnidipine. If you have any heart or liver problem kindly find some alternative of Cilnidipine. The effect of Cilnidipine is not known yet so do not take it if you are breastfeeding the baby. Do not share the medicine with other people.

CDSCO APPROVAL: Cilnidipine tablet 5mg approved by CDSCO in India in 21.06.2007. Cilnidipine tablet 10 mg is approved by CDSCO in 21.06.2007.

FORMULATIONS IN MARKET:
Cilnidipine 5 mg Tablets
Cilnidipine 10 mg Tablets
Cilnidipine 20 mg Tablets
Cilnidipine 5 mg + Telmisartan 20 mg Tablets
Cilnidipine10 mg + Telmisartan 40 mg Tablets
Cilnidipine 10 mg + Metoprolol Succinate 25 mg Tablets
Cilnidipine 10 mg + Metoprolol Succinate 50 mg Tablets
Cilnidipine 10 mg + Olmesartan Medoxomil 20 mg Tablets
Cilnidipine 10 mg + Olmesartan Medoxomil 40 mg Tablets
Cilnidipine 10 mg + Ramipril IP 10 mg Capsules
Cilnidipine 10 mg + Ramipril IP 2.5 mg Capsules
Cilnidipine 5 mg + Hydrochlorothiazide 12.5 mg + Telmisartan 40 mg capsules

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult