99% Pure Chemical Grade Loperamide Hydrochloride For Industrial Cas No: 34552-83-5

SR.NOTESTOBSERVATIONSPECIFICATION
1.DescriptionA white powderWhite to slightly yellow powder.
2.SolubilityCompliesFreely soluble in methanol and chloroform; slightly soluble in water and in dilute acids; very slightly soluble in isopropyl alcohol.
3.Melting point225.5Melts at above 225au C with some decomposition.
4.Identification by
A)I.R.
Complies
The match with working standards.
B)ChlorideCompliesShould comply as per USP 42
5.Loss on drying0.19NMT 0.5%w/w
6.Residue on Ignition0.06NMT 0.1% w/w
7.Organic Impurities by TLCCompliesThe spot from the sample solution corresponds in Rf value, color, and intensity to that from the standard solution, and no secondary spots are observed.
8.Assay by chemical99.5NLT 98.0%w/w and NMT 102.0% w/w on a dried basis
9.Residual solvents by GCHSBDL
121
BDL
BDL
BDL
BDL
BDL
BDLMethanol: NMT 3000 ppm
Acetone : NMT 5000 ppm
Isopropyl alcohol: NMT 5000 ppm
Tetrahydrofuran : NMT 720 ppm
Chloroform: NMT 60 ppm
Benzene : NMT 2 ppm

Methylene dichloride NMT 600 ppm