Fluconazole Ip/bp/usp/ep Cas No: 86386-73-4

Niksan Pharmaceutical is the largest manufacturer and exporter of the Fluconazole among all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the Fluconazole API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.
Niksan Pharmaceutical provides API and finished formulations of Fluconazole in all over Indian states Like Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Jammu Kashmir Etc.
Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Fluconazole in many countries for years. The countries where we exporting are Zambia, Haiti, Ghana, Kenya, Jamaica, Cameroon, Uganda, Zimbabwe, Nigeria, Tanzania, Trinidad & Tobago, Puerto Rico, Nepal, Lebanon, South Africa, United States, India, United Kingdom, Ireland, Canada, Bangladesh, Iraq, Pakistan, Philippines, United Arab Emirates, New Zealand, Malaysia, Sri Lanka, Australia, Poland, Jordan, Tunisia, Belgium, Algeria, Morocco, Singapore, Thailand, Indonesia, Romani, Saudi Arabia, Hong Kong, France, Vietnam, Hungary, Greece , Egypt, Israel, Switzerland, Taiwan, South Korea, Iran, Sweden, Netherlands, Colombia, Mexico , Brazil, Spain, Germany, Turkey, Italy, Russia and many more countries.
Fluconazole used in the treatment of fungal infection. It has anti-fungal activity and by this Fluconazole slows the growth of fungi that cause infection. Fluconazole used in many fungal infections like blastomycosis, cryptococcosis, pityriasis versicolor, dermatophytosis, candidiasis, coccidiodomycosis.
SYNONYMS: Diflucan, Difluconazole, Fluconazol, Fluconazole, Fluconazolum, Triflucan.

IUPAC NAME: 2-(2, 4-difluorophenyl)-1, 3-bis (1H-1, 2, 4-triazol-1-yl) propan-2-ol

CAS NO: 86386-73-4
FORMULA: C13H12F2N6O
MOLECULAR MASS: 306.27 g/mol
STORAGE CONDITION: Store in cool and dry place. Keep medicine away from direct light and heat. Do not put medication in bathroom or any humid place. Keep away from children and pets.

HOW TO USE: Take medication orally ne time day. If you are taking the oral solution, kindly shake well before use. To get more benefits of the mass: 306.27 g/mol medicine take medicine regularly. Take your doctora s advice if you have any confusion regarding to the medication.

HOW FLUCONAZOLE WORKS: Fluconazole reduce the growth of the fungi by degrading or destroying the cell wall of fungi and by this action fungus cells cana t perform any other activity and by this Fluconazole gives the antifungal activity.

PHARMACOKINETICS: 90%Fluconazole absorbed after the oral administration, although the absorption may comparable in oral dose and by IV dose. Fluconazole takes 3hours to reach the peak plasma concentration. The protein binding of Fluconazole is very low, only 11-12% of Fluconazole binds with the blood plasma protein. The half-life of Fluconazole is approximately 30hours. Approximately 80% of unchanged drug eliminated by the urination and remaining metabolites eliminated by the feces.

SIDE EFFECTS OF FLUCONAZOLE: The common side effects like nausea, vomiting, dizziness, stomach pain, hair loss, stomach upset my seen in patients. If you see some serious side effects like renal problem, loss of appetite, weight loss, tiredness contact your doctor. Fluconazole rarely cause liver damage so if you see symptoms like stomach or abdominal pain see medical attention.

PRECAUTIONS: If you have allergic reaction from Fluconazole or any other azoles kindly tell your doctor. Fluconazole may cause fainting, dizziness, irregular heartbeats so if you have any heart problem tell your doctor. Share your family history if they have any sugar problem.

CDSCO APPROVAL: Fluconazole (2%) + Zinc Pyrethione (1%) suspension approved by CDSCO in India in 22.02.2005,
Fluconazole Dispersible tablets 50mg approved by CDSCO in India in 22.04.2008,
Framycetin + Hydrocortisone + Fluconazole topical cream approved by CDSCO in India in 1987-April,
Fluconazole tablet 300mg (Additional strength) approved by CDSCO in India in 28.11.2011,
Fluconazole 400mg tablet approved by CDSCO in India in 03.03.2005,
Fluconazole + Secnidazole + Azithromycin approved by CDSCO in India in 07.06.1999,
Fluconazole for Oral suspension 50/200 mg per 5ml (Pack Size: 35ml) approved by CDSCO in India in 20.08.2010,
Fluconazole + Zinc Pyrethrone (Each 30/60ml bottle contains: 2% + 1%) Lotion approved by CDSCO in India in 15.09.2008,
Fluconazole eye drops approved by CDSCO in India in 04.02.1998,
Fluconazole tablets approved by CDSCO in India in April-2004
Fluconazole approved by CDSCO in India in 29.05.2000,
Posaconazole Oral Suspension 40mg/ml approved by CDSCO in India in 18.07.2009,
Fluconazole capsules/injection approved by CDSCO in India in 28.01.1993,
Fluconazole tabs/caps/inj. approved by CDSCO in India in 26.04.1993,
Fluconazole tab approved by CDSCO in India in 2003,
Fluconazole topical gel (0.5%) approved by CDSCO in India in 13.08.2004.

FORMULATION AVAILABLE IN MARKET:
Fluconazole (2%) + Zinc Pyrethione (1%) suspension
Fluconazole Dispersible tablets 50mg
Framycetin + Hydrocortisone + Fluconazole topical cream
Fluconazole tablet 300mg (Additional strength)
Fluconazole 400mg tablets
Fluconazole + Secnidazole + Azithromycin tablets
Fluconazole for Oral suspension 50/200 mg per 5ml
Fluconazole + Zinc Pyrethrone (Each 30/60ml bottle contains: 2% + 1%) Lotion
Fluconazole eye drops
Fluconazole capsules
Fluconazole injection
Fluconazole topical gel (0.5%)

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult