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1 Year Member Since : 1 Year Hebei, China ... More B No.52 Zhaiying South street,Yuhua Dostrict, Shijiazhuang, China, Shijiazhuang, Hebei, 050000, China
Cas.:496775-62-3,Eltrombopag Olamine
Product Details

Cas.:496775-62-3,Eltrombopag Olamine

Product Code - 496775-62-3
Price : 1-20 USD ($)
Minimum Order Quantity : 1 Gram/Grams
  • Offered By :SHIJIAZHUANG DINGMIN PHARMACEUTICAL SCIENCES CO., LTD.
  • Product Added On :Jul 25, 2019
  • Last Updated On :Jul 26, 2019
  • Last Updated On :DM
Product Specifications :-
  • Molecular Weight
  • Purity(%)99
  • Chemical Name3-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid compd. with 2-aminoethanol
  • TypePharmaceutical Intermediates
  • Structural FormulaC29H36N6O6
  • Molecular FormulaC29H36N6O6
  • Physical FormPowder
  • SmellNo Smell
  • Ph Level7
  • StorageRoom Temperature
  • Appearancewhite powder
  • CAS No496775-62-3
  • UsageEltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
  • Color
  • EINECS No629-876-8
  • TasteOdorless
  • Shelf Life2 Years
  • Heavy Metal (%)<10ppm
  • GradeMedicine Grade
  • Medicine NameEltrombopag Olamine
  • HS Code2918990090
Trade Information :-
  • Main Export Market(s)Africa, Western Europe, South America, North America, Central America, Asia
  • Sample PolicyWithin a certain price range free samples are available
  • Supply Ability100 kgs Per Month
  • FOB Portany port in China
  • Packaging Detailsas per request
  • Payment TermsPaypal, Letter of Credit at Sight (Sight L/C), Days after Acceptance (DA), Cash in Advance (CID), Cash Against Delivery (CAD)
  • CertificationsISO9001
  • Delivery Time1 Week
  • Main Domestic MarketAll India
Salient Features of Cas.:496775-62-3,Eltrombopag Olamine :-
Product name Eltrombopag Olamine

Cas number 496775-62-3

Molecular formula C29H36N6O6

Molecular weight 564.63300

Appearance Powder
Specification
Item Standard Results
Identification A.H-NMR: comply with the structure

B.LC-MS: comply with the structure

C. The IR spectrum of sample should be identical with taht of reference standard

D.HPLC-ESI-MS: The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation ,as obtained in the assay. Complies

Complies

Complies


Complies
Heavy metals ≤10 ppm <10ppm
Water ≤1.0% 0.10%
Sulphated ash ≤0.5%, determined on 1.0 g. 0.01%
Related substances Unspecified impurities: for each impurity ≤0.1%
Total impurity ≤0.5% <0.10%
0.18%
Purity ≥99.0% 99.7%
Assay 99.0%~101.0% (anhydrous substance). 99.85%
Storage Preserve in well-closed, light-resistant and airtight containers. Complies
Function
Eltrombopag Olamine is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production.
About SHIJIAZHUANG DINGMIN PHARMACEUTICAL SCIENCES CO., LTD. :-

Shijiazhuang Dingmin Pharmaceutical Sciences Co., Limited is a professional company focusing on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. We have a R&D center and two plants in Shijiazhuang, Hebei Province. Our Products include active pharmaceutical ingredients (API), pharmaceutical and agrochemical intermediates and chiral compounds. We have won the trust of a wide range of customers/partners in the industry. Our major products are antineoplastic, cardiovascular and antibiotics and their intermediates.

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CONTACT DETAILS
SHIJIAZHUANG DINGMIN PHARMACEUTICAL SCIENCES CO., LTD.
B No.52 Zhaiying South street,Yuhua Dostrict, Shijiazhuang, China, Shijiazhuang, Hebei, 050000, China
Supplier:
Ms. Lily
General Manager
RFQ