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Telangana, India ... More 15-6-108 Afzal Gunj, Hyderabad, Telangana, 500012, India
Sertraline Hcl
Product Details

Sertraline Hcl

Product Code - 19
  • Offered By :TAJ PHARMACEUTICALS LTD.
  • Product Added On :Jul 16, 2019
Salient Features of Sertraline Hcl :-


Sertraline
Hcl


  • Molecular Formula
    C17H17Cl2N.HCl
  • Molecular Weight
    342.69
  • CAS Registry Number 79559-97-0

Chemical Name     
(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-met hyl-1-
                            
naphthalenamine  hydrochloride

Biological
Activity
    Potent, orally active selective serotonin re-uptake
inhibitor (SSRI) used  clinically to treat depression.

Synonyms:
(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE

HYDROCHLORIDE;(1S,4S)-4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE

HYDROCHLORIDE;(1S,4S)-1-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-4-(METHYLAMINO)NAPHTHALENE
HYDROCHLORIDE;N-(4(3,4-DICHLOROPHENYL)-3,4-DIHYDRO-1(2H)NAPHTHALIDENE)
METHANAMINE;SERTRALINE HCL FORM I;SERTRALINE HCL FORM II;SERTRALINE
HYDROCHLORIDE;SERTRALINE MANDELATE



Molecular
Formula:
C17H18Cl3N

Molecular Weight: 342.690520
[g/mol]

Product Group:  Antidepressant

Appearance:
White powder

Melting Point :  243-245

Solubility: 
Soluble in water;

Sertraline hydrochloride Chemical
Properties


mp: 246-249 °C

solubility:

DMSO: ~26 mg/mL

form: solid

color:  white

Merck
8467

CAS Data Base

Reference: 79559-97-0(CAS
DataBase Reference)

Assay:  More than 99.0%

Ecological
Information 
  Do not allow product to enter drinking water
supplies, waste water or soil!

Safety Information

Hazard
Codes
Xi

Risk Statements
36/37/38

Safety
Statements
22-24/25-36-26

WGK Germany
3

RTECS

QJ0352070

 Chemical data

  • Formula C17H17Cl2N
  • Mol. mass 306.229
    g/mol
  • SMILES eMolecules & PubChem
Pharmacokinetic
data

  • Bioavailability 44%
  • Metabolism
    N-demethylation (liver)
  • Half life
    Approximately 26 hours
  • Excretion Renal


Sertraline
hydrochloride Usage And Synthesis


Chemical Properties   
    White Crystalline Powder
Usage                            
  A selective serotonin reuptake inhibitor. Used as an antidepressant

Sertraline
hydrochloride Preparation Products And Raw materials


Raw
materials
    Thionyl chloride-->Aluminium
chloride-->METHYLAMINE-->Potassium tert-butanolate-->Diethyl
succinate-->3,4-Dichlorobenzophenone-->Sertraline-->3,4-Dichlorobenzoyl
chloride

Respiratory protection
required when dusts
are generated.

Industrial hygiene   
Immediately
change contaminated clothing. Wash hands and face after working with substance.
                                 

Hazards
Identification 
  
Not considered hazardous when handled under
normal conditions with good house keeping.
                                  



About TAJ PHARMACEUTICALS LTD. :-

Taj Pharmaceuticals Limited manufactures and distributes medicines. The company’s products include prescription solutions, lifesaving drugs, anti-cancer drugs, veterinary products, consumer brands, and CNS drugs. It focuses on medicines of anemia, anxiety disorders, cancer/oncology, ear infections, heart failure, hepatitis, HIV/AIDS, influenza, non-Hodgkin’s lymphoma, obesity, osteoporosis, Parkinson’s disease, pneumonia, transplantation, and common diseases. Taj Pharmaceuticals Limited was founded in 2004 and is headquartered in Mumbai, India.

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CONTACT DETAILS
TAJ PHARMACEUTICALS LTD.
15-6-108 Afzal Gunj, Hyderabad, Telangana, 500012, India
Supplier:
Mr S K. Singh
General Manager
RFQ