Rheological Additive for Pharmaceuticals General Description: Skygel™ Thickeners are colloidal, inorganic mineral thickeners which are essentially inert and non swelling in aqueous applications. When dispersed in water, they display unique Thixotropic properties that are useful in a variety of aqueous applications. Modest cost, high performance and virtually universal compatibility mean that they can often replace, or partially substitute for expensive imported thickeners while offering equivalent performance. Skygel™ thickeners are Hydrated Magnesium Aluminum Silicate base Pharmaceutical grade rheological additive refined from natural mineral clay. It has been developed as a high purity, fast hydrating stabilizer for aqueous systems. The therapeutic value of Attapulgite has been known for the last two centuries. However, scientific research into this amazing mineral’s therapeutic properties began in earnest in the 1950’s. It was discovered that specific thermal activation of this mineral could augment its adsorptive capacity and that different desirable properties could be developed. In pharmaceutical applications, their main use is in the field of intestinal medicine for the treatment of diarrhea because of their high sorptivity for toxins. Other uses include suspending, thickening, and tablet binding. Skygel™ in Pharmaceutical Applications In Antidiarrheal Medications Skygel™ pharmaceutical grade of Attapulgite is utilized in the

Skygelâ„¢ - 400 LVPH Rheological Additive for Pharmaceutical General Description Skygelâ„¢ Thickeners are colloidal, inorganic mineral thickeners which are essentially inert and non swelling in aqueous applications. When dispersed in water, they display unique Thixotropic properties that are useful in a variety of aqueous applications. Modest cost, high performance and virtually universal compatibility mean that they can often replace, or partially substitute for expensive imported thickeners while offering equivalent performance. Skygelâ„¢ thic