We offer paracetamol which is used as an analgesic and antipyretic. It is one of the active metabolite phenacetin. Unlike aspirin it does not have many side effects and thus used effectively for headaches, fever and other minor pain. Paracetamol is prepared in the following manner:

* Phenol is nitrated using sulfuric acid and sodium nitrate in mild condition.
* The para-isomer is separated from the ortho isomer by fractional distillation.
* The 4-nitrophenol is reduced to 4-aminophenol using a reducing agent such as sodium borohydride in basic medium.
* 4-aminophenol is reacted with acetic anhydride to give paracetamol.