1-Bromo-3,5-Dimethyladamantane
Posted on: 23rd September 2009
[China]
Name: 1-Bromo-3,5-dimethyladamantane
Synonyms: 1-Bromo-3,5-dimethyltricyclo[3.3.1.13,7]decane.
Molecular Formula : C12H19Br
Molecular Weight : 243.18
CAS Registry Number : 941-37-7
EINECS : 213-378-9
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Artensunate
Posted on: 7th April 2009
[India]
Artemisinin is under early research and testing for treatment of cancer, primarily by researchers at the University of Washington.[5][6] Artemisinin has a peroxide lactone group in its structure. It is thought that when the peroxide comes into contact with high iron concentrations (common in cancerous cells), the molecule becomes unstable and releases reactive oxygen species. It has been shown to
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Quinine Anhydrous
Posted on: 7th April 2009
[India]
Quinine was the first effective treatment for malaria caused by P. falciparum, appearing in therapeutics in the 17th century. It remained the antimalarial drug of choice until the 1940s, when other drugs took over. Since then, many effective antimalarials have been introduced, although quinine is still used to treat the disease in certain critical situations. Quinine is available with a prescripti
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Quinine
Posted on: 7th April 2009
[India]
Quinine was extracted from the bark of the South American cinchona tree and was isolated and named in 1817 by French researchers Pierre Joseph Pelletier and Joseph Bienaim Caventou. The name was derived from the original Quechua (Inca) word for the cinchona tree bark, "Quina" or "Quina-Quina", which roughly means "bark of bark" or "holy bark". Prior to 1820, the bark was first dried, ground to a f
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Amodiaquine
Posted on: 7th April 2009
[India]
Amodiaquine (trade names Camoquin, Flavoquine) is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent. Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like
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Amodiaquine
Posted on: 7th April 2009
[India]
Amodiaquine (trade names Camoquin, Flavoquine) is a 4-aminoquinoline compound related to chloroquine, used as an antimalarial and anti-inflammatory agent.
Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, l
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Dipyrone
Posted on: 7th April 2009
[India]
According to comments by Dr Anthony Wong of the University of So Paulo, Brazil in a WHO newsletter,[1] recent studies estimate that the incidence rate of metamizole-induced agranulocytosis is between 0.2 and 2 cases per million person days of use, with approximately 7% of all cases fatal (provided that all patients have access to urgent medical care). In other words, one should expect 50 to 500 de
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Propyphenazone
Posted on: 7th April 2009
[India]
Propyphenazone or Isopropylantipyrine (C14H18N2O, 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one) is a derivative of phenazone with similar analgesic and antipyretic effects.
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Metformin Hydrochloride
Posted on: 7th April 2009
[India]
Metformin (INN; trade names Glucophage, Riomet, Fortamet, Glumetza, Diabex, Diaformin, and others) (IPA: /m?t'f?rm?n/) is an oral anti-diabetic drug from the biguanide class. It is the first-line drug of choice for the treatment of type 2 diabetes, particularly in overweight and obese people and those with normal kidney function.[1][2][3] Metformin is the most popular anti-diabetic drug in the Uni
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Amodiaquine Hydrochloride
Posted on: 7th April 2009
[India]
Amodiaquine has been shown to be more effective than chloroquine in treating CRPF (chloroquine-resistant Plasmodium falciparum) malaria infections and may afford more protection than chloroquine when used as weekly prophylaxis. Amodiaquine, like chloroquine, is generally well tolerated. Although licensed, this drug is not marketed in the United States but is widely available in Africa. Its use, th
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Triclosan
Posted on: 7th April 2009
[India]
This organic compound is a white powdered solid with a slight aromatic/phenolic odor. It is a chlorinated aromatic compound which has functional groups representative of both ethers and phenols. Phenols often show anti-bacterial properties. Triclosan is only slightly soluble in water, but soluble in ethanol, diethyl ether, and stronger basic solutions such as 1 M sodium hydroxide, Triclosan can be
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Antipyrine
Posted on: 7th April 2009
[India]
Antipyretics are drugs that reduce body temperature in situations such as fever. However, they will not affect the normal body temperature if one does not have fever
Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
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Propacetamol Hydrochloride
Posted on: 7th April 2009
[India]
Propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid Diethylglycin. This has the advantage of making it more water soluble. It is used in post-operative care and is delivered by I.V.. [2] It is given if the patient is unable to take oral or rectally delivered paracetamol and non-steroidal anti-inflammatory drugs are contraindicat
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Phenazone Salicylate
Posted on: 7th April 2009
[India]
Propyphenazone or Isopropylantipyrine (C14H18N2O, 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one) is a derivative of phenazone with similar analgesic and antipyretic effects.
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Quinine Dihydrochloride
Posted on: 7th April 2009
[India]
In addition to its anti-malarial properties, quinine is an effective muscle relaxant, long used by the Quechua Indians of Peru to halt shivering brought on by cold temperatures. The Jesuit Brother Agostino Salumbrino (1561-1642), an apothecary by training and who lived in Lima, observed the Quechua using the quinine-containing bark of the cinchona tree for that purpose. While its effect in treatin
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Quinine Hydrochloride
Posted on: 7th April 2009
[India]
In addition to its anti-malarial properties, quinine is an effective muscle relaxant, long used by the Quechua Indians of Peru to halt shivering brought on by cold temperatures. The Jesuit Brother Agostino Salumbrino (1561-1642), an apothecary by training and who lived in Lima, observed the Quechua using the quinine-containing bark of the cinchona tree for that purpose. While its effect in treatin
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Sertraline Hydrochloride
Posted on: 7th April 2009
[India]
Sertraline hydrochloride (trade names Zoloft, Lustral) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily used to treat clinical depression in adult outpatients as well as obsessive-compulsive, panic and social anxiety disorders in both adults and children. In 2007 it was the most prescribed an
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Dichloralphenazone
Posted on: 7th April 2009
[India]
Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. This drug acts on the blood vessels in the
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Zolpidem Tartrate
Posted on: 7th April 2009
[India]
Zolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors.[1] It works quickly (usually within 15 minutes) and ha
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Primaquine
Posted on: 7th April 2009
[India]
Primaquine (or primaquine phosphate) is a medication used in the treatment of malaria and Pneumocystis pneumonia. It is a member of the 8-aminoquinoline group of drugs that includes pamaquine.
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Amodiaquine Base
Posted on: 7th April 2009
[India]
Artemisinin is under early research and testing for treatment of cancer, primarily by researchers at the University of Washington. Artemisinin has a peroxide lactone group in its structure. It is thought that when the peroxide comes into contact with high iron concentrations (common in cancerous cells), the molecule becomes unstable and releases reactive oxygen species. It has been shown to reduce
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Quinine Sulphate
Posted on: 7th April 2009
[India]
Quinine also played a significant role in the colonization of Africa by Europeans. As the dawn of modern pharmacology, Quinine was the prime reason why Africa ceased to be known as the white man's grave. According to socialist historian Clifford D. Conner in "A People's History of Science", "It was quinine's efficacy that gave colonist fresh opportunities to swarm into the Gold Coast, Nigeria and
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Isopropylantipyrine
Posted on: 7th April 2009
[India]
Propyphenazone or Isopropylantipyrine (C14H18N2O, 1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one) is a derivative of phenazone with similar analgesic and antipyretic effects.
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Ondansetron Hydrochloride
Posted on: 7th April 2009
[India]
Ondansetron (INN) (pronounced) or Zofran is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy. Its effects are thought to be on both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which activates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemorece
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Bisoprolol Fumarate
Posted on: 7th April 2009
[India]
Bisoprolol had an antihypertensive effect in all hypertension models investigated. Bisoprolol reduced the blood pressure in conscious dogs with renal hypertension, accompanied by only a slight decrease in heart rate. In comparison with bisoprolol, propranolol had a weaker antihypertensive effect even at a considerably higher dose level [12]. Bisoprolol also reduced the blood pressure in rats with
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